Downstream Research Associates – Process Development

BioTalent; Tustin (CA); On-site; USD 80,000 - 110,000; Full time

Benefits offered by this job

Competitive pay

Comprehensive benefits

Job summary

BioTalent is seeking a Research Associate or Lead Research Associate to advance downstream process development for biologics. The role focuses on purification of monoclonal antibodies and recombinant proteins and requires hands-on chromatography, filtration, and analytical technique experience.

Ideal candidates will drive process optimization, support tech transfer, and collaborate with cross-functional teams.

Qualifications

• Downstream process development background in biopharmaceuticals.
• Experience with monoclonal antibodies or recombinant proteins.
• Biopharmaceutical or CDMO experience preferred.

Responsibilities

• Lead downstream process development and optimization projects.
• Purify proteins using chromatography and filtration techniques.
• Operate ÄKTA/FPLC systems and perform analytical assays.
• Design experiments, analyze data, and report findings.
• Support scale-up and technology transfer to manufacturing.
• Collaborate with cross-functional teams globally.

Skills

Downstream Process Development

Monoclonal Antibodies

Recombinant Proteins

Tools

ÄKTA/FPLC systems

HPLC

SDS-PAGE

Job description

Research Associate & Lead Research Associate - Process Development (Downstream)

Join a team developing the next generation of biologic therapies! We're looking for talented scientists with downstream purification experience to support the development and optimization of processes for monoclonal antibodies, recombinant proteins, and other biologics.

We're hiring for two levels:

1-2 years of biopharmaceutical industry experience

Perfect for early-career professionals looking to grow their expertise in downstream process development.

3-4 years of biopharmaceutical industry experience

We're looking for a technical leader who can drive downstream process development, lead purification studies, troubleshoot complex challenges, support process scale-up and technology transfer, and serve as a subject matter expert within cross-functional teams.

What you'll be working on:

• Downstream process development and optimization
• Protein purification using chromatography and filtration
• Operating ÄKTA/FPLC systems
• HPLC, SDS-PAGE, A280, and other analytical techniques
• Experimental design, data analysis, and technical reporting
• Supporting scale-up and technology transfer to manufacturing

Ideal background:

• Downstream Process Development
• Monoclonal Antibodies or Recombinant Proteins
• Biopharmaceutical or CDMO experience

• Hourly pay, bonus, equity, and comprehensive benefits.
• Work on impactful products in a regulated, high-quality environment
• Collaborate with cross-functional global teams
• Grow your career in a dynamic and innovative organization

Work Authorization:

Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time