Process Development Engineer I, Cell Culture

BioSpace; Village of Tarrytown (NY); On-site; USD 80,000 - 131,000; Full time

Job summary

Regeneron, based in Tarrytown, NY, is seeking a Process Development Engineer to join the Cell Culture Development Group in PMPD. You will develop monoclonal antibody production processes, screen candidates, select cell lines, and optimize media and feeds, collaborating with cell line development, purification, analytics, and manufacturing teams.

This is a hands‑on role in a non‑GMP lab supporting early‑stage development, with responsibilities spanning design, data analysis, and technology

Qualifications

• BS or MS in Chemical Engineering or Bio-related Engineering with 0–2 years of laboratory experience.
• Excellent verbal and written communication and rigorous record-keeping for development data.
• Strong initiative to complete tasks and learn new technologies.
• Ability to work independently and in a team across multiple projects.
• Contribute to lab equipment maintenance and safety.

Responsibilities

• Design and develop cell culture studies from shaker flasks to 2–15 L bioreactors.
• Screen antibody candidates, select cell lines, and develop media and feeds.
• Prepare media, feeds, buffers, and operate bioreactor and analytical equipment.
• Analyze data statistically and manage critical development data.
• Collaborate with cell line development, scale‑up, purification, analytics, and manufacturing.
• Author development reports and review manufacturing records.
• Support technology transfer with process transmittals and on‑site support in Albany, NY.

Skills

Cell culture

Data analysis

Laboratory techniques

Ambr250

JMP

Education

BS or MS in Chemical Engineering or Bio-related Engineering

Tools

Ambr250

JMP

Job description

Build Our Future Together

At Regeneron, we use science and innovation to develop life‑changing medicines for people with serious diseases. We are seeking a Process Development Engineer to join our Cell Culture Development Group within Preclinical Manufacturing and Process Development (PMPD), supporting early‑stage development in a non‑GMP process development laboratory. In this role, you will develop production processes for monoclonal antibodies by screening top candidates, selecting cell lines, and developing media and feeds while collaborating with cell line development, purification, analytics, and manufacturing teams. This position offers the opportunity to contribute to a fast‑growing, science‑driven organization making a meaningful difference to patients worldwide.

When & Where

Location: Tarrytown, NY

Work model: On‑site

Discover Your Role

• Design and develop cell culture studies from shaker flasks to single-use and glass bench-scale bioreactors (2L to 15L)
• Screen top-tier antibody candidates, select cell lines, and develop media and feed formulations
• Prepare media, feeds, buffers, and reagents, and operate and maintain bioreactor and analytical equipment
• Analyze data statistically and manage critical data in a highly organized manner
• Partner with colleagues in cell line development, scale‑up, purification, analytics, and manufacturing
• Author development reports, document your work, and review manufacturing records
• Support technology transfer through written process transmittals, troubleshooting, and on‑site support for manufacturing campaigns in Albany, NY

Please note: this role requires weekend work and occasional travel to upstate NY

This Role Requires

• BS or MS in Chemical Engineering or Bio-related Engineering with 0–2 years of experience in a laboratory setting
• Excellent verbal and written communication skills, and record-keeping abilities to accurately record, analyze, and document development data
• Strong initiative and drive to complete ambitious tasks and learn new technologies
• You work well both independently and in a team, balancing multiple projects at once
• Contribute to lab equipment maintenance and safety to keep a safe, effective, and efficient working environment
• Preferred: Experience with mammalian cell culture
• Preferred: Experience developing fed‑batch bioreactor processes, including optimizing feeding strategies and evaluating cell culture media and feed formulations
• Preferred: Experience with ambr250 and with statistical design and analysis software (e.g., JMP)

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, colour, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centres, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)
$80,300.00 - $131,100.00