Process Development Engineer I, Cell Culture

Regeneron; Village of Tarrytown (NY); On-site; USD 90,000 - 130,000; Full time

Job summary

Regeneron Pharmaceuticals, Inc. in Tarrytown, NY is seeking a Process Development Engineer to join the Cell Culture Development Group within PMPD, supporting early-stage development in a non-GMP laboratory.

You will design and optimize production processes for monoclonal antibodies, screening candidates, selecting cell lines, and developing media and feeds with related teams. The role involves preparing media and feeds, operating bioreactors and analytical equipment, and analyzing data.

Qualifications

• BS or MS in Chemical Engineering or Bio-related Engineering with 0-2 years of laboratory experience.
• Excellent verbal and written communication skills and meticulous record-keeping.
• Strong initiative and ability to manage multiple tasks independently and in a team.
• Contribute to lab equipment maintenance and safety.

Responsibilities

• Design and develop cell culture studies from 2L to 15L bioreactors.
• Screen antibody candidates, select cell lines, and develop media and feeds.
• Prepare media, feeds, buffers, and reagents; operate bioreactor and analytics equipment.
• Analyze data statistically and manage critical data documentation.
• Collaborate with cell line development, scale-up, purification, analytics, and manufacturing teams.
• Author development reports and support tech transfer and on-site manufacturing campaigns.

Skills

Verbal and written communication

Record-keeping

Initiative and drive

Independent and team work

Lab equipment maintenance

Education

B.S. or M.S. in Chemical Engineering or related

Tools

ambr250

JMP

Job description

Build our future together

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Process Development Engineer to join our Cell Culture Development Group within Preclinical Manufacturing and Process Development (PMPD), supporting early-stage development in a non-GMP process development laboratory. In this role, you will develop production processes for monoclonal antibodies by screening top candidates, selecting cell lines, and developing media and feeds while collaborating with cell line development, purification, analytics, and manufacturing teams.

When & where

Location: Tarrytown, NY. Work model: On-site.

Discover your role

• Design and develop cell culture studies from shaker flasks to single-use and glass bench-scale bioreactors (2L to 15L)
• Screen top-tier antibody candidates, select cell lines, and develop media and feed formulations
• Prepare media, feeds, buffers, and reagents, and operate and maintain bioreactor and analytical equipment
• Analyze data statistically and manage critical data in a highly organized manner
• Partner with colleagues in cell line development, scale-up, purification, analytics, and manufacturing
• Author development reports, document your work, and review manufacturing records
• Support technology transfer through written process transmittals, troubleshooting, and on-site support for manufacturing campaigns in Albany, NY

Please note: this role requires weekend work and occasional travel to upstate NY.

This role requires

• BS or MS in Chemical Engineering or Bio-related Engineering with 0-2 years of experience in a laboratory setting
• Excellent verbal and written communication skills, and record-keeping abilities to accurately record, analyze, and document development data
• Strong initiative and drive to complete ambitious tasks and learn new technologies
• You work well both independently and in a team, balancing multiple projects at once
• Contribute to lab equipment maintenance and safety to keep a safe, effective, and efficient working environment

Preferred

• Experience with mammalian cell culture
• Experience developing fed-batch bioreactor processes, including optimizing feeding strategies and evaluating cell culture media and feed formulations
• Experience with ambr250 and with statistical design and analysis software (e.g., JMP)

We are committed to building a workplace with an inclusive culture.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g., medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based.