Process Development Engineer I, Cell Culture

Regeneron Pharmaceuticals, Inc (USA); Village of Tarrytown (NY); On-site; USD 80,000 - 131,000; Full time

Job summary

Regeneron Pharmaceuticals, Inc (USA) in Tarrytown, NY seeks a Process Development Engineer to advance cell culture development for monoclonal antibodies in a non-GMP lab. You will screen candidates, select cell lines, and optimize media/feed strategies while collaborating with cross-functional teams.

The role requires a BS or MS in Chemical or bio-related engineering with 0–2 years in a lab, strong communication, and initiative. Weekend work and occasional travel to upstate NY are noted.

Qualifications

• BS or MS in Chemical Engineering or bio-related Engineering with 0–2 years of laboratory experience.
• Excellent verbal and written communication and strong record-keeping abilities.
• Self-motivated, proactive, and capable of balancing multiple projects.

Responsibilities

• Design and develop cell culture studies from shaker flasks to 2L–15L bench-scale bioreactors.
• Screen antibody candidates, select cell lines, and develop media and feed formulations.
• Prepare media, feeds, buffers, and reagents; operate bioreactor and analytical equipment.
• Analyze data statistically and manage critical data meticulously.
• Collaborate with cell line development, scale-up, purification, analytics, and manufacturing teams.
• Author development reports and review manufacturing records; support tech transfer and on-site manufacturing campaigns in Albany, NY.

Skills

Verbal communication

Written communication

Record-keeping

Initiative

Teamwork

Lab safety

Education

BS or MS in Chemical Engineering or bio-related engineering

Tools

Ambr250

JMP

Bioreactors

Job description

Build our future together: At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Process Development Engineer to join our Cell Culture Development Group within Preclinical Manufacturing and Process Development (PMPD), supporting early-stage development in a non-GMP process development laboratory. In this role, you will develop production processes for monoclonal antibodies by screening top candidates, selecting cell lines, and developing media and feeds while collaborating with cell line development, purification, analytics, and manufacturing teams. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide. When & where: Location: Tarrytown, NY Work model: On-site

Discover your role:

• Design and develop cell culture studies from shaker flasks to single-use and glass bench-scale bioreactors (2L to 15L)
• Screen top-tier antibody candidates, select cell lines, and develop media and feed formulations
• Prepare media, feeds, buffers, and reagents, and operate and maintain bioreactor and analytical equipment
• Analyze data statistically and manage critical data in a highly organized manner
• Partner with colleagues in cell line development, scale-up, purification, analytics, and manufacturing
• Author development reports, document your work, and review manufacturing records
• Support technology transfer through written process transmittals, troubleshooting, and on-site support for manufacturing campaigns in Albany, NY

Note: this role requires weekend work and occasional travel to upstate NY.

This role requires:

• BS or MS in Chemical Engineering or Bio-related Engineering with 0-2 years of experience in a laboratory setting
• Excellent verbal and written communication skills, and record-keeping abilities to accurately record, analyze, and document development data
• Strong initiative and drive to complete ambitious tasks and learn new technologies
• You work well both independently and in a team, balancing multiple projects at once
• Contribute to lab equipment maintenance and safety to keep a safe, effective, and efficient working environment

Preferred:

• Experience with mammalian cell culture
• Experience developing fed-batch bioreactor processes, including optimizing feeding strategies and evaluating cell culture media and feed formulations
• Experience with ambr250 and with statistical design and analysis software (e.g., JMP)

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship. Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter. Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about on-site expectations for your role and location. As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications. For jobs in Canada: this posting is for an existing position. Salary Range (annually) $80,300.00 - $131,100.00 Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.