Principal Translational Biomarkers Scientist

MSD Malaysia

Rahway (NJ)

Hybrid

USD 173,000 - 273,000

Full time

5 days ago

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Benefits offered by this job

Hybrid work arrangements

Job summary

Merck & Co., Inc. in Rahway, NJ seeks a Principal Scientist to provide strategic biomarker leadership across Neuroscience programs, spanning translational and clinical biomarker strategies from early to late development.

The role emphasizes decision-centric plans integrating mechanism, biology, pharmacodynamics, and patient heterogeneity to drive clinical decisions. The successful candidate will lead integrated translational biomarker programs, mentor scientists, and communicate strategies to

Qualifications

Education: Ph.D., M.D., or equivalent advanced scientific degree with 10+ years of relevant experience in neuroscience, translational medicine, neurobiology, biomarker science, drug development, or a related discipline.

Responsibilities

Develop and lead integrated biomarker strategies across Neuroscience programs, in partnership with cross-functional development teams.
Translate disease biology and therapeutic mechanism into translational hypotheses and fit-for-purpose biomarker approaches.
Define how biomarkers can inform key development questions including proof of biology, target engagement, dose and regimen selection, patient stratification, response assessment, and go/no-go decisions.
Serve as the biomarker representative on cross-functional program teams and provide strategic biomarker input to program-level decision making.