Principal Scientist, Spatial Genomics & Multiomics

Biopharma Careers; Cambridge (MA); On-site; USD 117,000 - 201,000; Full time

Job summary

Johnson & Johnson is seeking a Principal Scientist, Spatial Omics, for Multiomics Discovery in Cambridge, MA or Spring House, PA. The role combines strategic leadership with hands-on execution in spatial genomics to advance therapeutic discovery in neuroscience, oncology, and immunology.

You will design, optimize, and deploy molecular, phenotypic, and spatial assays to generate robust data. Ideal candidates have 6+ years in biotech/pharma, deep spatial omics expertise, and proven ability to lead

Qualifications

• Six or more years in biotech/pharma industry.
• Proven high-impact scientific deliverables (publications, talks).
• Deep technical spatial omics expertise and end-to-end workflow understanding.

Responsibilities

• Lead development and validation of spatial genomics assays for neuroscience, oncology, and immunology.
• Design workflows including tissue processing, ISH, microscopy, imaging and sequencing.
• Scale laboratory infrastructure and lead multiple experimental platforms.

Skills

Spatial omics

Genomics

CRISPR perturbation

Data analysis

Communication

Education

PhD in Genetics/Genomics/Molecular Biology

Tools

Bruker CosMx

10x Genomics Visium

Pooled screening

Job description

Johnson & Johnson is seeking a Principal Scientist, Spatial Omics, for Multiomics Discovery in Cambridge, MA or Spring House, PA. The role combines strategic leadership with hands-on execution in spatial genomics to advance therapeutic discovery in neuroscience, oncology, and immunology.

You will design, optimize, and deploy molecular, phenotypic, and spatial assays to generate robust data. Ideal candidates have 6+ years in biotech/pharma, deep spatial omics expertise, and proven ability to lead