Principal Scientist – Oligonucleotide Process Development

Amgen; United States; On-site; USD 150,000 - 210,000; Full time

Job summary

Amgen is hiring a Principal Scientist in Oligonucleotides to lead the development of manufacturing processes for oligonucleotide drug substances. You will guide technology transfer to GMP facilities, drive process innovation, and mentor staff within a dynamic Process Development group.

The role is based at Amgen's campuses in Thousand Oaks, CA or Cambridge, MA and involves collaboration with cross-functional teams to advance pipeline programs.

Qualifications

• PhD/PharmD/MD with 2+ years scientific experience
• Master's degree with 5+ years scientific experience
• Bachelor's degree with 7+ years scientific experience

Responsibilities

• Lead a multidisciplinary project team in the development of sustainable and cost-effective processes for oligonucleotide manufacturing.
• Work with cross-functional teams to develop strategies and implementation plans to expand production capacity and improve yield.
• Drive oligonucleotide technology innovation
• Support cGMP manufacturing and technology transfer to GMP production facilities
• Develop strategies to ensure process performance through process understanding, modeling and characterization
• Guide successful completion of project deliverables and ensure timelines are met
• Work cross-functionally to deliver regulatory documents and support regulatory filings
• Serve as a technical expert and keep current in the field of bioconjugate manufacturing
• Coach and provide career and scientific / technical advice to colleagues within the organization

Skills

Oligonucleotide process development

GMP manufacturing

Technology transfer

Leadership

Cross-functional collaboration

Education

PhD/MD/PharmD

Master's degree

Bachelor's degree

Job description

Amgen is hiring a Principal Scientist in Oligonucleotides to lead the development of manufacturing processes for oligonucleotide drug substances. You will guide technology transfer to GMP facilities, drive process innovation, and mentor staff within a dynamic Process Development group.

The role is based at Amgen's campuses in Thousand Oaks, CA or Cambridge, MA and involves collaboration with cross-functional teams to advance pipeline programs.