Principal Scientist Medicinal Chemistry - San Diego, CA

VetJobs; San Diego (CA); On-site; USD 148,000 - 180,000; Full time

Job summary

VetJobs is seeking a Principal Scientist in Medicinal Chemistry for their San Diego location. This role involves designing and synthesizing new cancer treatment therapies and leading interdisciplinary teams. Candidates should have a Ph.D. in related fields and proven experience in pharmaceutical research, with strong leadership and communication skills.

Qualifications

• Must have strong skills in synthetic organic and peptide chemistry.
• 5+ years experience in pharmaceutical/biotech R&D environments.
• Experience in targeted cancer therapy modalities preferred.

Responsibilities

• Design and synthesize small molecule/peptide compounds.
• Lead SAR efforts on assigned projects.
• Supervise junior scientists and ensure high-quality work.

Skills

Synthetic organic chemistry

Peptide chemistry

Data analysis

Leadership

Interpersonal skills

Education

Ph.D in synthetic organic, peptide, or medicinal chemistry

MS with 10+ years experience

Job description

Principal Scientist Medicinal Chemistry - San Diego, CA

Join to apply for the Principal Scientist Medicinal Chemistry - San Diego, CA role at VetJobs

Principal Scientist Medicinal Chemistry - San Diego, CA

Join to apply for the Principal Scientist Medicinal Chemistry - San Diego, CA role at VetJobs

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Job Description

Job Description

ATTENTION MILITARY AFFILIATED JOB SEEKERS - Our organization works with partner companies to source qualified talent for their open roles. The following position is available to Veterans, Transitioning Military, National Guard and Reserve Members, Military Spouses, Wounded Warriors, and their Caregivers. If you have the required skill set, education requirements, and experience, please click the submit button and follow the next steps. Unless specifically stated otherwise, this role is "On-Site" at the location detailed in the job post.

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Job Description

The Principal Scientist will design and synthesize novel chemical constructs as potential new RPT therapies for cancer treatments. This position will require a highly motivated and an experienced medicinal chemist with strong synthetic organic and/or peptide chemistry skills. The role will offer an opportunity to work as functional lead on multiple projects ranging from target selection through candidate nomination stages and can be expected to lead early-stage projects in an interdisciplinary setting. The role is highly technical and will need a person who enjoys leading from the bench with high productivity and data analysis skills and a comfort level in working under tight timelines. The role requires an ability and willingness to manage both internal and external chemistry personnel.

Job Responsibilities

Essential duties and responsibilities include the following. Other duties may be assigned.

Design and synthesize small molecule/peptide compounds in support of SAR campaigns for pipeline projects.

Lead SAR efforts on assigned projects, design and synthesize key target molecules to assess chemical/biological hypothesis.

Work in close collaboration with interdisciplinary teams to provide functional chemistry leadership to guide programs through lead identification/optimization phases.

Work closely with biology, DMPK, imaging and in vitro/vivo teams to ensure that target compounds are generated in a timely manner to support the screening funnel.

Supervise the work of junior scientists and ensure experimental rigor and high quality.

Regularly present research findings and project updates to interdisciplinary teams.

Keep abreast of the literature in the field of RPTs, identify novel concepts and ideas to help advance the state of art in RPT field.

Participate in intellectual property filings and the preparation of publications and presentations.

Identify external partners, KOLs, outside expertise that will help advance the pipeline.

Serve as the scientific lead for external partnerships, collaborations and lead scientific projects through outsourcing if needed.

Adhere rigorously to safety guidelines, regulatory standards and company policies and ensure a safe working environment.

Auto req ID

448230BR

Minimum Education Required

Ph. D

Job_Category

Scientific Research & Development

Additional Qualifications/Responsibilities

Education and Experience

PhD in synthetic organic, peptide or medicinal chemistry with 5+ years of experience or MS 10+ years in pharmaceutical/biotech R&D environments demonstrating successful accomplishments and progressive leadership and broadening responsibilities.

Experience in working on targeted cancer therapy modalities such as RPTs, ADCs, PDCs is highly desirable.

Skills And Qualifications

Experience in leading small molecule/peptide projects from screening hit to development candidate.

Demonstrated ability to supervise and effectively guide the work of junior scientists and has managed external chemistry resources.

Strong interpersonal, organizational and communication skills and ability to motivate and drive productivity in small company environments. Prior experience as a chemistry leader or functional leader on interdisciplinary team is critical.

Well versed in modern synthetic organic/peptide/med chem principles and demonstrated track record of high productivity and achievements in the lab.

High scientific curiosity and a learning mindset coupled with strong technical problem-solving skills and strong understanding of the concepts of drug design, SAR analysis, ADME/PK is important.

The ability to share data and collaborate with cross functional team members is critical as is the ability to effectively interpret data and plan experiments without supervision.

Excellent written and oral communication and presentation skills and ability to work in a fast-paced, dynamic, and collaborative environment.

Physical Demands

While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 30 pounds. Specific vision abilities required by this job include close vision and distance vision.

This is a position that requires working in a laboratory environment, protective clothing, gloves, and safety glasses are required while working in a laboratory environment.

Work Environment

The noise level in the work environment is usually moderate.

The starting compensation for this job is a range from $148,000 - $179,300 plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.

City*

San Diego

State*

California

Job Code

Pharmaceutical Pharmaceutical

Affiliate Sponsor

Bristol Myers Sqibb BMS

Salary Range

>$100,000

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

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