Sr. Scientist I, Biochemcial Assay Development

BPS Bioscience Inc.; San Diego (CA); On-site; USD 100,000 - 160,000; Full time

Job summary

Une entreprise de recherche biomédicale recherche un Sr. Scientist I pour développer des assays biophysiques et enzymatiques. En tant que membre clé de l'équipe R&D, vous participerez à l'innovation de nouveaux produits et améliorerez les assays existants. Vous apporterez une expertise significative en cinétique enzymatique et serez en mesure de travailler avec une équipe dynamique pour relever des défis de recherche.

Benefits

401k with 4% company match

Medical/Dental/Vision health insurance plans

Vacation and paid holidays

Companywide lunches provided quarterly

Qualifications

• Ph.D. avec plusieurs années d'expérience en industrie ou formation postdoctorale.
• Expérience confirmée dans la cinétique enzymatique et l'optimisation des assays.
• Capacité à travailler de manière autonome avec un minimum de supervision.

Responsibilities

• Proposer et gérer des projets de recherche sur des assays biochimiques et cellulaires.
• Développer des stratégies expérimentales spécifiques au projet et exécuter les procédures établies.
• Préparer des rapports de recherche et présenter les résultats lors de réunions d'équipe.

Skills

Enzymology

Assay Development

Protein/Protein Interactions

Fluorescence

Luminescence-Based Assays

Problem-Solving

Communication Skills

Independent Work

Education

Ph.D. in Biochemistry, Biophysics, Molecular Biology, or related field

Tools

Microsoft Applications (Word, Excel, PowerPoint, GraphPad Prism)

Job description

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Job Overview

BPS Bioscience Inc. is a leading provider of recombinant proteins, assay kits, and recombinant cell lines for drug discovery. We are seeking an exceptional scientist, with a strong background in enzymology, enzyme kinetics, protein/protein interactions, and fluorescence and luminescence-based assays.

Job Overview

BPS Bioscience Inc. is a leading provider of recombinant proteins, assay kits, and recombinant cell lines for drug discovery. We are seeking an exceptional scientist, with a strong background in enzymology, enzyme kinetics, protein/protein interactions, and fluorescence and luminescence-based assays.

The Senior Scientist I will work in a laboratory environment, conducting research and experiments for non-clinical research. He/She will be a pivotal member of R&D Team supporting team scientific research tasks to expand company product portfolio. This person will work closely with a team of scientists to help develop novel or to improve existing biochemical in-vitro and cell-based assays. His/her duties will include enzyme characterization, enzymatic assay development, protein/protein interaction assays, and assessing enzyme inhibitor potency and mode of inhibition mechanism. This person is expected to drive the effectiveness of research and maintain a high level of expertise through the study of scientific literature, knowledge of competitors' products, and attendance at seminars.

The candidate must be experienced in enzymology and assay development and other biochemical and molecular biology techniques. This person should be able to work independently with minimum guidance and perform experiments to a very high standard, troubleshoot technical and scientific problems, and effectively progress multiple projects simultaneously.

Responsibilities

• Propose, plan, and manage research projects related to development of biochemical and cell-based assays.
• Assess new technologies and future applications of technologies to expand company product portfolio.
• Developing project-specific experimental strategies and techniques and executing established procedures (Designing experiments, performing compound screening, assisting other groups, and interacting with customers through electronic means).
• Supporting R&D Team in identification and monitoring new trends, concepts and original approaches for key pathways and hot targets for drug discovery.
• Supporting transfer of technology to QC and Screening service Teams as well as supporting these teams in their routine work.
• Troubleshooting and conducting processes for assays improvement.
• Preparing research reports/ presentations and presenting findings at regular team meetings, brainstorming meetings, and for external audiences.
• Attending a scientific conference to gain knowledge of new research areas and translate to our new product lines.
• Maintaining excellent working relationships with partners throughout the company.
• Maintaining updated and well-organized lab notebooks.
• Other tasks and duties as assigned.
  
  

Requirements

• A Ph.D. degree in Biochemistry, Biophysics, Molecular Biology, Cell Biology, or a related field with several years of Industry experience or postdoctoral training is required.
• The candidate must have proven experience performing enzyme kinetics and assay optimization.
• Hands-on experience with various biochemical enzymatic assays and in vitro protein-protein binding assays (ELISA, AlphaLisa, TR-FRET, FP etc) is essential.
• Previous hands-on experience in developing cell-based assays is preferred but not required.
• A background in cell culture is a plus.
• Strong problem-solving skills and a proactive attitude towards exploring new approaches.
• Must be able to work independently with supervision as needed.
• Adaptable / Flexible - willing and able to adjust to multiple demands and shifting priorities and meet day-to-day challenges with confidence and professionalism.
• Excellent written and oral communication skills for effective presentation of complex scientific data to cross-functional teams and senior level scientists.
• Self-motivated with excellent interpersonal and organizational skills with the ability to take a hands-on approach to work effectively in a dynamic and collaborative, fast-paced environment.
• Strong teamwork-oriented, open to collaboration with internal and external collaborators.
• Knowledge of computer software and Microsoft applications (Word, Excel, PowerPoint, GraphPad Prism).
  
  

Benefits!

• 401k with 4% company match
• Medical/Dental/Vision health insurance plans
• Vacation and paid holidays
• Companywide lunches provided quarterly
  
  

BPS Bioscience is an equal opportunity employer, without regard to race, color, religion, age, gender, sexual orientation, disability, or any other characteristic protected by applicable law.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

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