Principal Scientist (Lab Head), Mass Spectrometry Based Biomarkers

Boehringer Ingelheim GmbH; Ridgefield (CT); On-site; USD 141,000 - 211,000; Full time

Job summary

Boehringer Ingelheim seeks a Principal Scientist (Lab Head) in Mass Spectrometry Based Biomarkers to lead discovery programs in the Drug Discovery Sciences (DDS) department. You will guide MS biomarker strategy, mentor scientists, and collaborate across global project teams to advance candidate programs toward clinical development.

You will design and execute MS-based experiments, oversee small molecules and protein biomarker quantitation, and drive innovations in analytical workflows within a

Qualifications

• PhD in biochemistry, pharmacology or related scientific discipline.
• 5+ years in preclinical drug discovery with matrix leadership responsibilities.
• Experience leading employees and projects (1–3 years).
• Strong biomarkers translational sciences and pharmacological principles.

Responsibilities

• Review BM discovery and quantitation requests and align with project partners.
• Act as scientific leader for MS Biomarker function in cross-functional teams.
• Lead design, execution, and analysis of MS-based experiments (small molecules, protein biomarkers).
• Operate MS platforms (Orbitrap, timsTOF, Sciex QQQ) and related analysis software.
• Develop and optimize mass spectrometry-based targeted quantitation workflows.
• Drive innovations and lead global team strategies to advance projects.
• Mentor and develop scientists in a high-performing research environment.

Skills

Mass spectrometry

Biomarkers

Leadership

Scientific communication

Education

PhD in biochemistry/pharmacology or related

Tools

Orbitrap

timsTOF

Sciex QQQ

Job description

Principal Scientist (Lab Head), Mass Spectrometry Based Biomarkers

Description

We are seeking a highly motivated Principal Scientist to join our global Mass Spectrometry-based Biomarker team within the Drug Discovery Sciences (DDS) department. You’ll work at the cutting edge of drug discovery - shaping breakthrough therapies and making an immediate impact.

You will work in global multidisciplinary project teams generating high-impact results that directly impact decision-making and help advance innovative drug candidates toward clinical development. This opportunity combines scientific excellence, strategic thinking, and people leadership with the advancement of next-generation biomarker capabilities in a collaborative global research environment.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunities for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the company’s success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities

• In this role, you will review requests for BM discovery & quantitation, decide on resources & align the purpose and path-forward with our partners in project teams
• Act as a scientific leader and key representative of the MS Biomarker function in cross-functional project teams, contributing to projects in discovery research.
• Lead the design, execution, and analysis of mass spectrometry-based experiments, including small molecules, protein Biomarker quantitation and in vitro proteomics.
• Expertise in operating cutting-edge mass spectrometry platforms (Orbitrap, Bruker timsTOF, Sciex QQQ.) and expert understanding of respective analysis software.
• Hands-on experience with establishing and implementing mass spectrometry based targeted quantitation methods, developing and optimizing innovative analysis workflows.
• Independently drive innovations, lead the development and implementation of global team strategies/initiatives to advance projects.
• Lead, mentor and develop scientists within a high-performing and collaborative research environment.

Requirements

• PhD in biochemistry, pharmacology or related scientific discipline 5 years or more of experience in preclinical drug discovery, including (matrix) leadership responsibilities
• One (1) to three (3) years´ experience leading employees and projects is required.
• Track record as a scientific representative in discovery projects, with the ability to influence project direction in an industry setting
• Strong understanding of biomarkers, translational sciences, biochemical mechanisms, and pharmacological principles relevant to drug discovery
• Deep expertise in mass spectrometry-based applications, with strong experience with small molecule quantitative/targeted workflows. Demonstrated ability to solve complex drug discovery challenges
• Analytical mindset with experience in sample preparation from cells and tissues for LC-MS analyses
• Solid understanding of proteomics approaches for cell pharmacology relevant to drug discovery
• Forward-looking mindset, with a passion for advancing mass spectrometry-based applications for better impact in drug discovery
• Excellent presentation skills, stakeholder management and ability to present concepts outside of expertise area

Eligibility Requirements:

• Must be legally authorized to work in the United States without restriction.
• Must be willing to take a drug test and post-offer physical (if required)
• Must be 18 years of age or older

Compensation Data

The base salary range for this position is $140,800 to $211,200. The position may be eligible for a role-specific discretionary bonus, relocation assistance, and/or other compensation elements. We continuously review market data and may adjust salary ranges as needed in the future. Actual compensation will be based on job-related factors such as skills, experience, qualifications, and other factors permitted by law. Benefits include medical, dental, and vision coverage, retirement savings opportunities, paid time off, paid holidays, disability and life insurance benefits, and other company-sponsored benefits. For additional information regarding our benefits and Total Rewards offerings, please click here .