Principal Scientist (Lab Head), Mass Spectrometry Based Biomarkers

BioCT Innovation Commons; Ridgefield (CT); Híbrido; USD 141.000 - 211.000; Jornada completa

Descripción de la vacante

Boehringer Ingelheim seeks a Principal Scientist to lead the Mass Spectrometry Biomarker effort within Drug Discovery Sciences. You will guide discovery projects, develop MS-based biomarker strategies, and mentor team members in a globally distributed setting.

The role emphasizes leadership, collaboration with partners, and advancing quantitative MS workflows to support preclinical to clinical development. A strong track record in MS and biomarker translational science is required.

Formación

• PhD in biochemistry, pharmacology or related scientific field with 5+ years in preclinical drug discovery
• Experience leading employees and projects in discovery settings
• Strong biomarker and translational science knowledge relevant to drug discovery
• Extensive mass spectrometry expertise including targeted quantitation workflows
• Experience with sample prep for LC-MS analyses
• Excellent presentation and stakeholder management skills

Responsabilidades

• Review BM discovery and quantitation requests and align with project teams
• Lead MS Biomarker function representation in cross-functional projects
• Design, execute, and analyze MS-based experiments for small molecules and biomarker quantitation
• Operate Orbitrap, Bruker timsTOF, and Sciex QQQ platforms and corresponding software
• Develop and optimize MS-based targeted quantitation methods and workflows
• Drive innovations and strategic initiatives for the global team
• Mentor and develop scientists in a collaborative research environment

Conocimientos

Mass spectrometry

Biomarkers

Leadership

Project management

LC-MS analysis

Educación

PhD in biochemistry or related field

Herramientas

Orbitrap

Bruker timsTOF

Sciex QQQ

Descripción del empleo

Description

We are seeking a highly motivated Principal Scientist to join our global Mass Spectrometry-based Biomarker team within the Drug Discovery Sciences (DDS) department. You’ll work at the cutting edge of drug discovery - shaping breakthrough therapies and making an immediate impact.

You will work in global multidisciplinary project teams generating high-impact results that directly impact decision-making and help advance innovative drug candidates toward clinical development. This opportunity combines scientific excellence, strategic thinking, and people leadership with the advancement of next-generation biomarker capabilities in a collaborative global research environment.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunities for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the company’s success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities

• In this role, you will review requests for BM discovery & quantitation, decide on resources & align the purpose and path-forward with our partners in project teams
• Act as a scientific leader and key representative of the MS Biomarker function in cross-functional project teams, contributing to projects in discovery research.
• Lead the design, execution, and analysis of mass spectrometry-based experiments, including small molecules, protein Biomarker quantitation and in vitro proteomics.
• Expertise in operating cutting-edge mass spectrometry platforms (Orbitrap, Bruker timsTOF, Sciex QQQ.) and expert understanding of respective analysis software.
• Hands-on experience with establishing and implementing mass spectrometry based targeted quantitation methods, developing and optimizing innovative analysis workflows.
• Independently drive innovations, lead the development and implementation of global team strategies/initiatives to advance projects.
• Lead, mentor and develop scientists within a high-performing and collaborative research environment.

Requirements

• PhD in biochemistry, pharmacology or related scientific discipline 5 years or more of experience in preclinical drug discovery, including (matrix) leadership responsibilities
• One (1) to three (3) years´ experience leading employees and projects is required.
• Track record as a scientific representative in discovery projects, with the ability to influence project direction in an industry setting
• Strong understanding of biomarkers, translational sciences, biochemical mechanisms, and pharmacological principles relevant to drug discovery
• Deep expertise in mass spectrometry-based applications, with strong experience with small molecule quantitative/targeted workflows. Demonstrated ability to solve complex drug discovery challenges
• Analytical mindset with experience in sample preparation from cells and tissues for LC-MS analyses
• Solid understanding of proteomics approaches for cell pharmacology relevant to drug discovery
• Forward-looking mindset, with a passion for advancing mass spectrometry-based applications for better impact in drug discovery
• Excellent presentation skills, stakeholder management and ability to present concepts outside of expertise area

Eligibility Requirements:

• Must be legally authorized to work in the United States without restriction.
• Must be willing to take a drug test and post-offer physical (if required)
• Must be 18 years of age or older

Compensation Data

This position offers a base salary typically between $140,800.00 and $211,200.00 USD. The position may be eligible for a role specific variable or performance based bonus and or other compensation elements.