Principal Scientist, High-Content Imaging & AI Analytics

Johnson & Johnson Co.

Spring House (PA)

On-site

USD 160,000 - 210,000

Full time

8 hours ago
Be an early applicant

Get a reply from this employer

Your resume and cover letter, tailored to exactly what they’re hiring for.

Get past ATS filters

Job summary

Johnson & Johnson in Spring House, PA seeks a Principal Scientist in High-Content Imaging to advance therapeutic discovery across Immunology, Neuroscience, and Oncology portfolios. You will design end-to-end imaging workflows on 2D/3D models, develop assays, and collaborate with internal teams and external partners to drive data-driven insights.

The role requires hands-on lab work, development of new assays, and strong communication with cross-functional teams. A Ph.D.

Qualifications

  • Ph.D. in Biochemistry, Systems biology, Human biology or related discipline is required.
  • 4+ years of pharmaceutical industry experience is required.
  • Deep, technical high-content imaging expertise required with end-to-end workflows.
  • Excellent written and oral communication skills required.
  • Ability to work across disciplines and translate high-dimensional readouts into biology insights.

Responsibilities

  • Apply state-of-the-art drug discovery approaches in a multidisciplinary team.
  • Develop, optimize, and validate high-content imaging and other assays for Immunology, Neuroscience, Oncology programs.
  • Establish and refine new molecular assays and workflow development.
  • Collaborate with teams to translate readouts into actionable biological insights.
  • Work with CROs/external partners to ensure data quality and timely deliverables.
  • Support data workflows including data mapping, QC, and analytical handoffs to computational teams.

Skills

High-content imaging
Image analysis
Programming (Python/R)
Cross-functional collaboration
Verbal & written communication

Education

Ph.D. in Biochemistry or related field

Job description

Johnson & Johnson in Spring House, PA seeks a Principal Scientist in High-Content Imaging to advance therapeutic discovery across Immunology, Neuroscience, and Oncology portfolios. You will design end-to-end imaging workflows on 2D/3D models, develop assays, and collaborate with internal teams and external partners to drive data-driven insights.

The role requires hands-on lab work, development of new assays, and strong communication with cross-functional teams. A Ph.D.

Get your free, confidential resume review.

or drag and drop your file here.

Similar jobs

Similar jobs worth comparing

Lead Scientist, High-Content Imaging & Drug Discovery
Lead Scientist, High-Content Imaging & Drug Discovery

Johnson & Johnson Innovative Medicine • Spring House (PA)

On-site
USD 150,000 - 190,000
Principal Scientist, High-Content Imaging
Principal Scientist, High-Content Imaging

Johnson & Johnson Innovative Medicine • Spring House (PA)

On-site
USD 150,000 - 190,000
Principal Scientist, High-Content Imaging
Principal Scientist, High-Content Imaging

Johnson & Johnson Co. • Spring House (PA)

On-site
USD 160,000 - 210,000
Principal Scientist, Imaging AI for Oncology
Principal Scientist, Imaging AI for Oncology

Johnson & Johnson Co. • New Brunswick (NJ)

On-site
USD 117,000 - 201,000
Vacation 120 hours
Sick time 40 hours
Holiday pay 13 days
+2
Principal Scientist, Oncology Discovery & Immunology
Principal Scientist, Oncology Discovery & Immunology

Johnson & Johnson Co. • Spring House (PA)

On-site
USD 180,000 - 240,000
Lead Imaging AI Scientist for Oncology Trials
Lead Imaging AI Scientist for Oncology Trials

Johnson & Johnson Co. • Spring House (PA)

On-site
USD 117,000 - 201,000
Vacation 120 hours / year
Sick time 40 hours / year
Holiday pay 13 days / year
+1
Principal Scientist — Agentic Cheminformatics & Workflows
Principal Scientist — Agentic Cheminformatics & Workflows

Johnson & Johnson Innovative Medicine • Spring House (PA)

On-site
USD 117,000 - 201,000
Vacation up to 120 hours/year
Sick time up to 40 hours/year
Holiday pay and time off
Senior Imaging AI Scientist — Oncology (Hybrid)
Senior Imaging AI Scientist — Oncology (Hybrid)

Johnson & Johnson Co. • Cambridge (MA)

On-site
USD 109,000 - 175,000
Vacation 120 hours
Sick time
Holiday pay
+4
Imaging AI Scientist for Oncology Trials
Imaging AI Scientist for Oncology Trials

Johnson & Johnson Co. • Raritan (NJ)

On-site
USD 117,000 - 201,000
Vacation –120 hours per year
Sick time – 40 hours per year
Holiday pay – 13 days per year
+2
Imaging AI Scientist, Oncology Trials Lead
Imaging AI Scientist, Oncology Trials Lead

Johnson & Johnson Co. • Cambridge (MA)

On-site
USD 117,000 - 201,000
Vacation time
Sick leave
Holiday pay
+5