Principal Scientist – Discovery Genomics & Oncology (Multi-Omics)

SLAS (Society for Laboratory Automation and Screening); Boston (MA); On-site; USD 156,000 - 189,000; Full time

Benefits offered by this job

Comprehensive benefits

Flexible Time Off

Paid holidays and vacation

Job summary

Bristol Myers Squibb is seeking a Principal Scientist to join the Discovery Biosciences Genomics team in Cambridge Crossing, MA, focusing on multi-omics approaches for oncology target discovery and translational research. You will apply cutting-edge genomics technologies and functional assays to advance drug discovery programs.

The role emphasizes wet-lab work, cross-functional collaboration, and developing novel strategies to identify and validate targets, with leadership across projects in a

Qualifications

• Bachelor’s degree with 8+ years of academic and/or industry experience.
• Master’s degree with 6+ years of academic and/or industry experience.
• Ph.D. or equivalent advanced degree with 4+ years of experience.

Responsibilities

• Conduct full-time laboratory-based research supporting target identification and oncology drug discovery.
• Design, develop and optimize genomics and functional assays to evaluate candidates and mechanism of action.
• Implement novel genomic assays including single-cell RNA-seq and spatial transcriptomics.
• Execute CRISPR screening and model engineering to support translational research.
• Collaborate across Discovery Biology, Predictive Sciences, Computational Genomics and other groups.
• Maintain ELN/LIMS documentation and present findings in reports/publications.
• Train and assist team members in a matrixed environment.

Skills

Genomics

Single-cell RNA-seq

Spatial transcriptomics

CRISPR screening

Cancer biology

Data analysis

Education

Bachelor’s Degree

Master’s Degree

Ph.D. or equivalent advanced degree

Tools

Jira

LIMS

Confluence

Job description

Bristol Myers Squibb is seeking a Principal Scientist to join the Discovery Biosciences Genomics team in Cambridge Crossing, MA, focusing on multi-omics approaches for oncology target discovery and translational research. You will apply cutting-edge genomics technologies and functional assays to advance drug discovery programs.

The role emphasizes wet-lab work, cross-functional collaboration, and developing novel strategies to identify and validate targets, with leadership across projects in a