Principal Scientist / Associate Director Translational Informatics

AstraZeneca; New Haven (CT); Hybrid; USD 133,000 - 201,000; Full time

Job summary

An established industry player is seeking a visionary leader for the Principal Scientist / Associate Director role in Translational Informatics. This exciting position involves driving innovation through AI/ML and bioinformatics, focusing on biomarker development and drug re-purposing strategies. Collaborating across various functions, you will lead efforts to integrate multi-modal data and deliver transformative insights. With a commitment to fostering a flexible and collaborative work environment, this role offers a unique opportunity to make a significant impact in the field of biomedical research and patient care.

Benefits

Bonuses

Equity

Retirement plans

Paid leave

Health coverage

Qualifications

• PhD or equivalent in Bioinformatics, Computational Biology, or related fields.
• 5+ years in pharma or biotech focusing on translational research.

Responsibilities

• Lead the Translational Informatics function and develop a data strategy.
• Collaborate with teams to translate omics and clinical data into hypotheses.

Skills

AI/ML methods for biomedical data analysis

Translational research

Bioinformatics

Genomics

Molecular biology

Communication skills

Education

PhD in Bioinformatics or related fields

Job description

Principal Scientist / Associate Director Translational Informatics

Join to apply for the Principal Scientist / Associate Director Translational Informatics role at AstraZeneca.

At AstraZeneca, we win through the science, which is at the heart of our success. We push the boundaries of science to deliver medicines, aiming to benefit patients and create value for shareholders. Our environment fosters collaboration and innovation, attracting top talent.

Introduction to role:

We are seeking a visionary Head of Translational Informatics to lead efforts in integrating multi-modal data for biomarker development, target discovery, and drug re-purposing strategies. As part of Alexion’s Bioinformatics and Data Sciences team, you will drive innovation through AI/ML, bioinformatics, and real-world data applications, collaborating across functions to deliver transformative insights.

Accountabilities:

1. Lead the Translational Informatics function and develop a data strategy for biomarker discovery, patient stratification, and therapeutic insights.
2. Collaborate with preclinical and clinical teams to translate omics, preclinical, and clinical data into hypotheses.
3. Develop AI/ML models for target discovery, drug re-purposing, and predictive analytics.
4. Build collaborations across research, clinical, regulatory, and commercial teams to align strategies.
5. Represent the company in external scientific forums and consortia.
6. Stay current with scientific literature and integrate new insights and technologies.

Essential Skills/Experience:

• PhD or equivalent in Bioinformatics, Computational Biology, AI/ML, Genomics, Systems Biology, Biomedical Informatics, or related fields.
• At least 5 years of experience in pharma, biotech, or academia focusing on translational research and informatics.
• Strong understanding of human genetics, molecular biology, pathways, and networks.
• Expertise in AI/ML methods for biomedical data analysis and interpretation.
• Experience in drug re-purposing using computational approaches.
• Hands-on experience with multi-omics datasets, clinical trial data, and RWD.
• Excellent communication and collaboration skills.

Desirable Skills/Experience:

• Experience in rare diseases is advantageous.
• Knowledge of knowledge graphs, network biology, or causal inference is a plus.
• Experience with clinical data integration and analysis.

We promote a flexible work environment with in-person collaboration at least three days a week, respecting individual flexibility. Join us to make a difference.

The annual base salary ranges from $133,970 to $200,954, with additional benefits including bonuses, equity, retirement plans, paid leave, and health coverage. Details will be provided upon offer.

At AstraZeneca, we value diversity and inclusion, fostering an environment where innovative ideas can emerge. Join us to transform lives.

Ready to make an impact? Apply now and be part of our journey.