Principal Engineer, Site Reliability

Lonza Group Ltd.; Bend (OR); On-site; USD 120,000 - 160,000; Full time

Benefits offered by this job

Comprehensive benefits

401(k) matching

Bonus program

Career growth

Biomanufacturing tech exposure

Job summary

Lonza Group Ltd. in Bend, Oregon, seeks a Principal Engineer, Site Reliability, to develop and lead reliability strategies that improve asset performance, uptime, and compliance in manufacturing operations.

You will partner with Manufacturing, Engineering, and Maintenance to drive root-cause investigations, data analysis, and KPI tracking, while supporting audits and new equipment projects. This is a fully site-based, in-person role at Lonza.

Qualifications

• Experience in reliability, maintenance, manufacturing, or operations.
• Proven ability to lead complex projects with cross-functional teams.
• Strong knowledge of mechanical and electrical systems.
• Experience using maintenance management and asset performance systems.
• Familiarity with cGMP environments and maintenance best practices.
• Strong problem-solving, analytical, and communication skills.
• Ability to influence stakeholders in a regulated setting.

Responsibilities

• Develop and lead reliability strategies to improve asset performance and uptime.
• Collaborate with Manufacturing, Engineering, and Maintenance to support site goals.
• Lead root cause investigations and reliability improvement initiatives.
• Analyze maintenance and asset performance data to identify trends.
• Optimize spare parts strategies and criticality assessments.
• Establish and monitor reliability KPIs and report to senior leadership.
• Support audits and new equipment projects for long-term reliability.

Skills

Reliability engineering

Maintenance management

Cross-functional collaboration

Mechanical systems

Electrical systems

Problem solving

Communication skills

Stakeholder influence

Tools

CMMS

Job description

The actual location of this job is in Bend, Oregon (USA). Relocation assistance is available for eligible candidates and their families, if needed.

As the Principal Engineer, Site Reliability, you will play a critical role in supporting the reliable production of life-changing medicines. Working closely with Engineering and Maintenance teams, you will develop and drive reliability strategies that improve equipment performance, increase system uptime, and support safe, compliant manufacturing operations. This is a fully site-based role. Working together in person supports close, real-time collaboration and the technical precision needed to manufacture medicines to the highest quality and safety standards.

What you will get

• An agile career and dynamic working culture.
• An inclusive and ethical workplace.
• Compensation programs that recognize high performance.
• Participation in the Lonza bonus program, rewarding company and individual success.
• Comprehensive medical, dental, vision, life, and disability insurance from day one.
• A competitive 401(k) program with company matching contributions.
• Opportunities to work with advanced biomanufacturing technologies and grow through cross-functional collaboration.

What you will do

Develop and lead reliability strategies that improve asset performance, equipment uptime, and operational efficiency. Partner with Manufacturing, Engineering, and Maintenance teams to support site goals and regulatory compliance. Lead root cause investigations and reliability improvement initiatives to prevent recurring equipment failures. Analyze maintenance and asset performance data to identify trends and improve reliability programs. Optimize asset criticality assessments and spare parts strategies to support business continuity. Establish and monitor reliability and maintenance KPIs and communicate results to senior leadership. Support audits, continuous improvement activities, and new equipment projects to ensure long-term reliability and maintainability.

What we are looking for

• Significant experience in reliability, maintenance, engineering, manufacturing, or operations environments.
• Experience leading complex projects and collaborating with cross-functional teams.
• Strong knowledge of mechanical and electrical systems and equipment reliability practices.
• Experience using maintenance management and asset performance systems to support decision-making.
• Knowledge of cGMP environments, engineering standards, and maintenance best practices.
• Strong problem-solving, analytical, and communication skills.
• Ability to influence stakeholders and drive continuous improvement in a regulated manufacturing environment.

About Lonza

Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there's no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that's the kind of work we want to be part of. Innovation thrives when people from all backgrounds bring their unique perspectives to the table.

At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law.

If you're ready to help turn our customers' breakthrough ideas into viable therapies, we look forward to welcoming you on board.

Every day, our teams across the world work together to turn scientific breakthroughs into life-changing medicines that reach up to 100 million patients a year.

Lonza is a place where people can make a unique impact, grow their careers and belong.

You will feel at home at Lonza if you:

• Take ownership, step forward, and enjoy meaningful responsibility
• Love solving problems and thrive in a complex, fast-moving environment
• Are curious, always looking to learn and improve
• Work collaboratively, contributing to something bigger than yourself
• Are motivated to make a difference through work that impacts customers and their patients

Why Lonza: We are a place of unique opportunity, where your ideas, expertise and ambition can make a real difference. Here, will have the freedom to grow, the support to succeed and the chance to contribute to work that matters. We are the makers of the medicines of tomorrow. Join us. Be you.