Principal Electrical Systems Engineer — Genomics Tools

Pacific Biosciences

Menlo Park (CA)

On-site

USD 180,000 - 240,000

Full time

6 days ago
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Job summary

Pacific Biosciences is seeking a Principal Electrical Systems Engineer to oversee the electrical system architecture of advanced sequencing instruments. You will lead system-level design across boards, cabling, and power, partnering with firmware, software, manufacturing, and quality teams to deliver robust, scalable instrument designs.

Responsibilities include defining system block diagrams, designing cables and harnesses, prototyping complex boards with FPGAs and microcontrollers, and driving

Qualifications

  • Bachelor's degree or higher in Electrical Engineering with 8–14 years of related experience.
  • Hands-on PCB design/layout using Altium, Cadence, or similar EDA tools.
  • Experience with USB, CAN, EtherCAT in electronic architectures; supplier collaboration.

Responsibilities

  • Create and maintain instrument system-level electronic block diagrams.
  • Design, prototype, and validate cables, wire harnesses, and connectors for production.
  • Prototype and validate mixed-signal boards with processors, FPGA, and power electronics.
  • Lead design reviews and work with NPI, Manufacturing, and suppliers for production.
  • Ensure compliance with UL, CE, FCC/EMC, IEC, FDA where applicable.

Skills

Leadership
Troubleshooting
Cross-functional collaboration
Hands-on debugging
Communication skills

Education

Bachelor's degree or higher in Electrical Engineering

Tools

Altium
Cadence
Oscilloscopes
Logic analyzers
DMMs
Power supplies

Job description

Pacific Biosciences is seeking a Principal Electrical Systems Engineer to oversee the electrical system architecture of advanced sequencing instruments. You will lead system-level design across boards, cabling, and power, partnering with firmware, software, manufacturing, and quality teams to deliver robust, scalable instrument designs.

Responsibilities include defining system block diagrams, designing cables and harnesses, prototyping complex boards with FPGAs and microcontrollers, and driving

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