Principal Data Engineer, AI-Driven Research Lead

Vir Biotechnology, Inc.; San Francisco, Northern (CA, KY); Hybrid; USD 177,000 - 247,000; Full time

Job summary

Vir Biotechnology, Inc. is seeking an Associate Director, Principal Data Engineer in San Francisco, with three days in the office weekly.

You will lead scalable data, cloud, software, and AI-enabled research platforms to accelerate scientific discovery, clinical data analysis, and program decisions. Ideal candidates will have extensive data engineering and cloud experience, expertise with Python/Java, and a track record of delivering AI-enabled scientific applications with governance and

Qualifications

• 12+ years of experience in data engineering, software engineering, scientific computing, cloud architecture, or scientific application.

Responsibilities

• Build AI-enabled research workflows and agents that help scientists search, analyze, summarize, and connect Vir-generated data.
• Develop AI agents for TCE research insights, Experimenta QC/QA review, and scientific/regulatory reporting.
• Design trusted LLM, RAG, knowledge-search, and agentic AI workflows with traceability, validation, governance, and human oversight.
• Lead development and integration of scientific platforms and data pipelines for bioinformatics and clinical data.
• Architect and operate AWS cloud infrastructure for AI/ML, bioinformatics, clinical analysis, and large-scale data.

Skills

Python

Java

AWS cloud

Data pipelines

LLM/RAG

Governance

Collaboration

Leadership

Education

BS/MS in Computer Science or related field

Data Engineering/Bioinformatics

Tools

SeqAssembler

HPD/dAIsY

SASTRY

OPAL Miner

Databricks

Snowflake

Redshift

Airflow

Job description

Vir Biotechnology, Inc. is seeking an Associate Director, Principal Data Engineer in San Francisco, with three days in the office weekly.

You will lead scalable data, cloud, software, and AI-enabled research platforms to accelerate scientific discovery, clinical data analysis, and program decisions. Ideal candidates will have extensive data engineering and cloud experience, expertise with Python/Java, and a track record of delivering AI-enabled scientific applications with governance and