Principal Cybersecurity Platform Architect

Vertex Pharmaceuticals Inc (US); Boston (MA); Hybrid; USD 147,600 - 221,400; Full time

Benefits offered by this job

Competitive compensation

Medical, dental, and vision coverage

Retirement savings programs

Paid time off

Wellness and EAP

Professional development

Inclusive culture

Job summary

Vertex Pharmaceuticals is seeking a Principal Cybersecurity Engineer, Core Security Infrastructure, to lead design, implementation, and hardening of foundational security platforms across network, cloud, application, AI, SaaS, and hybrid environments. This role requires deep technical leadership and hands-on expertise to enable secure modernization while maintaining resilience and compliance.

The successful candidate will partner with cybersecurity, infrastructure, cloud, and enterprise

Qualifications

• Bachelor’s degree in Information Security, Computer Science, Information Technology, Engineering, or related field.

Responsibilities

• Lead design, engineering, and optimization of core security platforms across network, cloud, and hybrid environments.
• Act as senior technical expert for foundational security controls ensuring scalability and reliability.
• Develop and enforce security standards, guardrails, and architectural patterns.
• Mentor engineers and influence cross-functional security initiatives across the enterprise.

Skills

Zero Trust

Palo Alto Networks

Cloud security

Network security

Security architecture

Automation

Identity-based security

Platform governance

Education

Bachelor’s degree in Information Security/CS/IT or related field

Tools

Illumio

Obsidian

Armis

Job description

Vertex Pharmaceuticals is seeking a Principal Cybersecurity Engineer, Core Security Infrastructure, to lead design, implementation, and hardening of foundational security platforms across network, cloud, application, AI, SaaS, and hybrid environments. This role requires deep technical leadership and hands-on expertise to enable secure modernization while maintaining resilience and compliance.

The successful candidate will partner with cybersecurity, infrastructure, cloud, and enterprise