Principal Clinical Scientist

Alignerr; United States; Remote; CAD 96,000 - 165,000; Part time

Benefits offered by this job

Fully remote

Flexible hours

Contract extensions possible

Job summary

Alignerr is seeking a Principal Clinical Scientist to shape how AI trains and evaluates medical evidence by ensuring clinical data meets regulatory-grade standards for submissions. This remote, hourly contract role targets senior scientists who want to influence AI-driven research workflows.

You will design and review protocols, audit trial data for regulatory alignment, and provide actionable feedback to improve AI model reasoning on clinical evidence.

Qualifications

• Senior-level experience designing clinical trial protocols intended for regulatory submission.
• Experience interpreting clinical data for regulatory agencies (FDA/EMA or equivalent).
• Strong background in biostatistics or translational science and clinical research methodology.

Responsibilities

• Design and review clinical trial protocols for AI training datasets.
• Audit clinical trial results for accuracy and regulatory alignment.
• Evaluate AI-generated analyses for scientific soundness and regulatory compliance.
• Provide expert feedback to improve AI model reasoning on clinical data.

Skills

Clinical trial design

Regulatory submissions

Biostatistics

AI evaluation feedback

Job description

Principal Clinical Scientist (AI Training)

About The Role

What if your years of clinical trial expertise could directly shape how AI understands, evaluates, and reasons about medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring that the clinical data powering next-generation AI systems meets the same standards expected in real-world regulatory submissions.

This is a fully remote, flexible contract role designed for experienced clinical scientists who want to work at the intersection of medicine and frontier AI.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulatory-grade datasets for AI training
• Interpret and audit clinical trial results for accuracy, consistency, and alignment with regulatory standards
• Evaluate AI-generated clinical analyses for scientific soundness and compliance with FDA, EMA, or equivalent agency expectations
• Provide expert, structured feedback that directly improves how AI models reason about clinical trial data, outcomes, and evidence
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level experience designing clinical trial protocols intended for regulatory submission
• Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent
• Strong background in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold AI outputs to the same standards you'd apply to a real submission
• Clear and confident communicator who can translate complex clinical concepts into actionable feedback

Nice to Have

• Prior experience with data annotation, data quality review, or AI evaluation systems
• Background in pharmacovigilance, medical affairs, or clinical operations
• Familiarity with AI tools or content evaluation workflows
• Experience working across multiple therapeutic areas or regulatory jurisdictions

Why Join Us

• Work directly on frontier AI systems that are reshaping clinical and biomedical research
• Influence how AI understands, evaluates, and applies real-world clinical evidence
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Collaborate with world-leading AI research teams and labs on high-impact projects
• Potential for ongoing work and contract extension as new projects launch