Postdoctoral Scholar in Stem Cell Disease Modeling and Precision Medicine

Laplace Expert Ltd; Berkeley, Northern (CA, KY); Hybrid; USD 69,000 - 77,000; Full time

Job summary

Innovative Genomics Institute at UC Berkeley seeks a Postdoctoral Scholar to build stem-cell disease models and precision-medicine platforms using genome engineering, CRISPR screening, single-cell multi-omics and AI. The role combines wet-lab stem cell work with-scale genomics and computational analysis to uncover disease mechanisms.

The position advances iPSC-derived disease models, contributes to NIH/NSF grants, mentors students, and collaborates across teams in a two-year appointment with

Qualifications

• PhD or equivalent international degree required by start date.
• Demonstrated expertise in cell biology, genetics, genomics or stem-cell biology preferred.
• Experience with multi-omics, CRISPR screens, iPSC disease modeling, genome engineering, or AI-based omics/imaging analysis desirable.

Responsibilities

• Engineer and differentiate human iPSCs into disease-relevant cell types.
• Validate models using tissue culture, PCR, sequencing, imaging and biochemical assays.
• Lead CRISPR screening campaigns from library design to production and analysis.
• Develop computational pipelines for multi-modal phenotypic data and AI modeling.

Skills

Scientific writing

Scientific communication

Student mentoring

Grant development

Research collaboration

Education

PhD or equivalent international degree

Tools

CRISPR screening

iPSC disease modeling

Genome engineering

AI-based omics/imaging analysis

Job description

Postdoctoral Scholar in Stem Cell Disease Modeling and Precision Medicine

University of California, Berkeley · Innovative Genomics Institute, Advanced Translational Genetics Lab

California, United States

Apply by 15 Oct 2026

About This Opportunity

The Innovative Genomics Institute at UC Berkeley is recruiting a postdoctoral scholar in the Advanced Translational Genetics Lab to build stem-cell disease models and precision-medicine discovery platforms using genome engineering, CRISPR screening, single-cell multi-omics and AI. Applications close on 14 October 2026 at 11:59 PM Pacific Time.

This postdoctoral position integrates experimental stem-cell engineering with scaled functional genomics and computational analysis to investigate the genetic and molecular basis of human disease. In the Advanced Translational Genetics Lab, the researcher will engineer and differentiate human induced pluripotent stem cells into disease-relevant cell types, validate models using tissue culture, PCR, next-generation sequencing, high-resolution imaging and biochemical assays, and run CRISPR screening campaigns from library design and cloning through lentiviral production and high-throughput perturbation. A third workstream centers on computational pipelines for multi-modal phenotypic data, pathway analysis and AI-based modeling to identify biological mechanisms and candidate therapeutic targets. Disease areas may include oncology, neurodevelopmental and neurodegenerative disorders, and metabolic disease. The postdoc will also mentor students, prepare manuscripts, present findings at conferences and contribute preliminary data and writing to NIH, NSF and private grant proposals. The appointment is two years with possible extension.

iPSC CRISPR screening precision medicine single-cell multi-omics genome engineering disease modeling AI modeling

Level Postdoc

Time Commitment Full-time

Duration Two years with possible extension based on performance and funding availability

Reference Code JPF05299

Field Stem Cell Disease Modeling and Precision Medicine

Specialization Biochemistry, Genetics and Molecular Biology

Organization Type University

Funding & Compensation

Amount USD 69073-77030

Funding Type Salary

Funding Status Paid

Requirements

Education

PhD or equivalent international degree is required by the appointment start date; applicants may be enrolled in a PhD programme at the time of application.

Experience

Demonstrated expertise in cell biology, genetics, genomics or stem-cell biology is preferred. Experience with multi-omics, CRISPR screens, iPSC disease modeling, genome engineering, or AI-based omics or imaging analysis is desirable, together with a strong publication record and excellent scientific communication.

General Skills Scientific writing Scientific communication Student mentoring Grant development Research collaboration

Languages

No more than three years of post-degree research experience by the appointment start date.