Postdoc - Stem Cell Disease Modeling and Precision Medicine - Innovative Genomics Institute

University of California-Berkeley; Berkeley (CA); On-site; USD 69,073 - 77,030; Full time

Job summary

The Innovative Genomics Institute at the University of California, Berkeley seeks applications for a Postdoctoral Scholar in the Advanced Translational Genetics Lab. The role focuses on stem cell disease modeling and precision medicine using iPSCs, CRISPR screening, and AI-driven data analyses.

Responsibilities include leading genome engineering projects, performing high-throughput sequencing and imaging, and mentoring students while contributing to grant proposals and manuscripts.

Qualifications

• PhD or equivalent degree; required by start date.
• Strong publication record and writing skills.
• Experience with stem cell biology and disease modeling preferred.

Responsibilities

• Lead genome engineering and differentiation of iPSCs into disease-relevant cell types.
• Design and execute CRISPR screens and validate models.
• Develop computational pipelines for multi-omics data and AI analyses.
• Mentor students and present findings at conferences.

Skills

Genome engineering

CRISPR screening

Multi-omics

AI modeling

Mentorship

Education

PhD in cell biology, genetics, genomics, or related field

Tools

NGS sequencing

PCR

Lentiviral production

Job description

Position Overview

Position title: Postdoc Scholar Employee-3252

Salary range: The UC postdoc salary scales set the minimum pay determined by experience level at appointment. See the following table(s) for the current salary scale(s) for this position: Table 23. A reasonable estimate for this position is $69,073 - $77,030.

Percent time: 100%

Anticipated start: Summer-Fall 2026

Position duration: 2 years with the possibility of extension based on performance and funding availability.

Application Window

Open date: April 22, 2026

Next review date: Monday, Jul 20, 2026 at 11:59pm (Pacific Time). Apply by this date to ensure full consideration by the committee.

Final date: Monday, Aug 3, 2026 at 11:59pm (Pacific Time). Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

The Innovative Genomics Institute at the University of California, Berkeley seeks applications for a Postdoctoral Scholar Employee in the Advanced Translational Genetics (ATG) Lab, in the area of stem cell disease modeling and precision medicine.

The ATG Lab investigates the genetic and molecular underpinnings of human disease through the integration of high-throughput pluripotent stem cell (PSC) models. By combining precise genome editing, automated cell engineering, and multiplexed CRISPR screening with single-cell multi-omics and AI modeling, we are building a state-of-the-art cell type-specific disease modeling that provide unique therapeutic discovery platforms. Our mission is to decode complex disease mechanisms and accelerate the development of precision medicine across a broad spectrum of conditions, including oncology, neurodevelopmental and neurodegenerative disorders, and metabolic diseases.

Responsibilities:

• Advanced Genome Engineering & Characterization
  • Lead projects under the guidance of the Principal Investigator that involve engineering, differentiation to disease relevant cell types and functional characterization of human induced pluripotent stem cells (iPSCs).
  • Execute complex molecular biology workflows, including large-scale tissue culture, PCR, NGS sequencing, high-resolution imaging, and biochemical functional assays to validate disease models.
• Scaled CRISPR Discovery
  • Design and execute sophisticated CRISPR screening campaigns, from library design and molecular cloning to lentiviral production.
  • Manage scaled cell culture operations to support high-throughput genetic perturbations and therapeutic discovery.
• Multi-Omic Data Integration & AI Modeling
  • Develop and implement computational pipelines to analyze multi-module phenotypic data.
  • Utilize pathway analysis and artificial intelligence (AI) modeling to derive biological insights and identify novel therapeutic targets from complex datasets.
• Mentorship & Collaboration
  • Provide technical guidance and professional mentorship to graduate and undergraduate students, fostering a collaborative and inclusive lab environment.
• Scientific Communication
  • Lead the preparation of high-impact manuscripts for peer-reviewed journals and present research findings at national and international conferences.
• Grant Development
  • Support the lab's sustainability by contributing preliminary data and strategic writing to federal and private grant proposals (e.g., NIH, NSF).

Qualifications

Basic qualifications (required at time of application)

• PhD (or equivalent international degree) or enrolled in a PhD degree program (or equivalent international degree).

Additional qualifications (required at time of start)

• Ph.D. (or equivalent international degree) required by the appointment start date.
• No more than three years of post-degree research experience by start date.

Preferred qualifications

• Excellent writing and communication skills.
• Strong publication record in peer reviewed journals.
• PhD in cell biology, biochemistry, genetics, genomics, or a related field.
• Demonstrated expertise in cell biology, genetics, genomics, or stem cell biology.
• Expertise with methods such as multi-omics, CRISPR screens, iPSC disease modeling, genome engineering, Artificial Intelligence model-based omics or imaging data analysis is desirable.

Application Requirements

Document requirements

• Curriculum Vitae - Your most recently updated C.V.
• Cover Letter
• Statement of Research

Reference requirements

• 3 required (contact information only)

Apply link: https://aprecruit.berkeley.edu/JPF05299

Help contact: [e-mail]

About UC Berkeley

UC Berkeley is committed to diversity, equity, inclusion, and belonging in our public mission of research, teaching, and service, consistent with UC Regents Policy 4400 and University of California Academic Personnel policy (APM 210 1-d). These values are embedded in our Principles of Community, which reflect our passion for critical inquiry, debate, discovery and innovation, and our deep commitment to contributing to a better world. Every member of the UC Berkeley community has a role in sustaining a safe, caring and humane environment in which these values can thrive.

The University of California, Berkeley is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.

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In searches when letters of reference are required all letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality prior to submitting their letter.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

Unless stated otherwise, unambiguously, in the position description, this position does not include sponsorship of a new consular H-1B visa petition that would require payment of the $100,000 supplemental fee.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment or discrimination, as defined by the employer.
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Job location

Berkeley, CA