Postdoctoral Scholar - Cellular and Molecular Physiology

The Pennsylvania State University; Hershey (PA); On-site; USD 50,000 - 80,000; Full time

Job summary

An established industry player is seeking a Postdoctoral Scholar to join a dynamic research team focused on neurodegenerative diseases. This role involves planning and executing experiments, analyzing data, and mentoring trainees. Candidates should have a strong background in Drosophila genetics and molecular techniques, with an excellent publication record. The position offers a unique opportunity to contribute to groundbreaking research in a collaborative environment, while also engaging in the academic community through manuscript preparation and grant writing. This is a limited-term appointment, promising a rewarding experience in a supportive and inclusive setting.

Qualifications

• Experience in Drosophila genetics and molecular techniques is essential.
• Strong publication record and ability to mentor junior trainees.

Responsibilities

• Plan and perform experiments in consultation with the PI.
• Analyze data using advanced statistical methods.
• Prepare manuscripts and grant proposals.

Skills

Drosophila genetics

Molecular techniques

Cellular metabolism

Behavioral assays

Bioinformatics

Statistical skills (R)

Education

PhD in relevant field

Tools

Statistical software (R)

Job description

APPLICATION INSTRUCTIONS:

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Job Description and Position Requirements:

A Postdoctoral Scholar position is available immediately in the Zarnescu laboratory in the Department of Cellular and Molecular Physiology at Penn State College of Medicine, Hershey, PA. The research focuses on the molecular mechanisms underlying neurodegenerative diseases (e.g., ALS, dementias) using Drosophila, cell-based models, and patient tissues. The lab also investigates environmental factors and gene-environment interactions affecting these diseases. A key area of research is to identify changes in translation and cellular metabolism using genetically encoded tools in various models (e.g., Coyne et al, Cell Reports 2017; Manzo et al, eLife 2019; Lehmkuhl et al, Acta Neuropathologica Comm 2021; Godfrey et al, Acta Neuropathologica Comm 2023).

The successful applicant should have experience and accomplishments in areas such as Drosophila genetics, molecular and cellular techniques (cloning, RNA/protein isolation, immunoprecipitations, immunofluorescence), cellular metabolism (mitochondrial biology), and behavioral assays. An excellent publication record is expected.

Job Responsibilities:

1. Planning, designing, and performing experiments in consultation with the PI.
2. Compiling and analyzing data using advanced statistical methods.
3. Supporting the PI in mentoring junior trainees.
4. Maintaining research data in laboratory notebooks, writing summaries, and communicating findings.
5. Preparing manuscripts and grant proposals.

Preferred Qualifications:

• Background in neuronal cell culture, including iPSCs, cell biology, molecular biology, biochemistry, and Drosophila neurobiology, genetics, and behavior.
• Bioinformatics and statistical skills (e.g., R, pathway analyses).
• Experience mentoring students.

This is a limited-term appointment funded for one year from the date of hire. A PhD in a relevant field is required.

Employment will require successful completion of background checks in accordance with university policies.

Additional Information:

The Pennsylvania State University is committed to diversity, equity, and inclusion, fostering a culture of inclusive excellence that supports all individuals.

Campus Security Crime Statistics:

Penn State publishes an Annual Security and Fire Safety Report (ASR) with crime statistics and policies, available here.

Employment requires successful background checks in accordance with university policies.

EEO Statement:

Penn State is an equal opportunity employer, committed to providing employment opportunities regardless of race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, or veteran status. For assistance due to disability, contact 814-865-1473.