Postdoctoral Research Fellow - DNA Repair & Genomics

Dana-Farber Cancer Institute (DFCI); Boston (MA); On-site; USD 72,000 - 76,000; Full time

Job summary

Dana-Farber Cancer Institute in Boston, MA seeks a Postdoctoral Research Fellow to join the D’Andrea Lab. The role focuses on the molecular basis of genomic stability and DNA repair mechanisms in human cancers, with access to advanced molecular biology tools and collaborations across disciplines.

The incumbent will design and execute experiments, use CRISPR/Cas9 and mass spectrometry, analyze data, and contribute to publications and grant applications within a dynamic team.

Qualifications

• PhD or MD in Molecular Biology, Cell Biology, Biochemistry, Genetics, or a related field.
• Experience with mammalian cell culture, protein purification, and molecular cloning.
• Excellent communication skills and ability to publish in peer-reviewed journals.

Responsibilities

• Design and conduct experiments related to DNA repair pathways, replication fork stability, and ubiquitin signaling.
• Use advanced techniques such as CRISPR/Cas9 gene editing, protein biochemistry, mass spectrometry, and live-cell imaging.
• Analyze data, interpret results, and present findings at internal and external scientific meetings.
• Collaborate with multidisciplinary teams, including medicinal chemists and clinical researchers.
• Contribute to manuscript writing and grant applications.
• Mentor junior team members and contribute to the overall research environment.

Skills

DNA repair

Cancer biology

Mammalian cell culture

Molecular cloning

Protein purification

CRISPR/Cas9

Mass spectrometry

Live-cell imaging

Education

PhD/MD required

Genetics/biochemistry background

Tools

CRISPR/Cas9

Mass spectrometry

Protein purification

Molecular cloning

Job description

Dana-Farber Cancer Institute in Boston, MA seeks a Postdoctoral Research Fellow to join the D’Andrea Lab. The role focuses on the molecular basis of genomic stability and DNA repair mechanisms in human cancers, with access to advanced molecular biology tools and collaborations across disciplines.

The incumbent will design and execute experiments, use CRISPR/Cas9 and mass spectrometry, analyze data, and contribute to publications and grant applications within a dynamic team.