Postdoctoral Fellow: D'Andrea Lab

Dana-Farber Cancer Institute; Boston (MA); Presencial; USD 72.000 - 76.000; Jornada completa

Descripción de la vacante

Dana-Farber Cancer Institute in Boston seeks a Postdoctoral Research Fellow for the D’Andrea Lab to explore the molecular basis of genomic stability and DNA repair mechanisms in human cancers. You will perform cutting-edge experiments, publish results, and contribute to the team’s scientific progress.

The role requires a PhD or MD and a strong background in DNA repair or cancer biology, with experience in mammalian cell culture and advanced molecular techniques.

Formación

• PhD or MD in Molecular Biology, Cell Biology, Biochemistry, Genetics, or a related field.
• Strong background in DNA repair, cancer biology, or chromatin biology is preferred.
• Experience with mammalian cell culture, protein purification, and molecular cloning.
• Excellent communication skills and ability to work both independently and in a team.
• Demonstrated ability to publish in peer-reviewed journals.

Responsabilidades

• Design and conduct experiments related to DNA repair pathways, replication fork stability, and ubiquitin signaling.
• Use advanced techniques such as CRISPR/Cas9 gene editing, protein biochemistry, mass spectrometry, and live-cell imaging.
• Analyze data, interpret results, and present findings at internal and external scientific meetings.
• Collaborate with multidisciplinary teams, including medicinal chemists and clinical researchers.
• Contribute to manuscript writing and grant applications.
• Mentor junior team members and contribute to the overall research environment.

Conocimientos

Communication skills

Teamwork

Publication record

Educación

PhD or MD

Herramientas

CRISPR/Cas9

Mass spectrometry

Live-cell imaging

Descripción del empleo

Postdoc Fellow: D'Andrea Lab
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Postdoctoral Research Fellow – D’Andrea Lab

Location: Dana-Farber Cancer Institute, Boston, MA

Qualifications

PhD or MD required

About Dana-Farber Cancer Institute

Located in the heart of Boston’s Longwood Medical Area, Dana-Farber Cancer Institute is a leading center for cancer research and treatment. As an affiliate of Harvard Medical School, Dana-Farber brings together internationally recognized scientists, physicians, and healthcare professionals in a shared mission to conquer cancer and related diseases. We are committed to discovery, innovation, and translating groundbreaking research into clinical practice—all in a collaborative and supportive environment.

Position Summary

The D'Andrea lab investigates chromosome instability and susceptibility to cancer. Our laboratory examines the molecular signaling pathways which regulate the DNA damage response in mammalian cells. Disruption of these pathways, by germline or somatic mutation, leads to genomic instability, cellular sensitivity to ionizing radiation, and defective cell cycle checkpoints and DNA repair. These pathways are often disrupted in cancer cells, accounting for the chromosome instability and increased mutation frequency in human tumors. We are seeking a highly motivated and talented Postdoctoral Research Fellow to join a dynamic team investigating the molecular basis of genomic stability and DNA repair mechanisms in human cancers. The candidate will work in a cutting-edge research environment with access to advanced molecular biology tools and technologies.

Key Responsibilities

• Design and conduct experiments related to DNA repair pathways, replication fork stability, and ubiquitin signaling.
• Use advanced techniques such as CRISPR/Cas9 gene editing, protein biochemistry, mass spectrometry, and live-cell imaging.
• Analyze data, interpret results, and present findings at internal and external scientific meetings.
• Collaborate with multidisciplinary teams, including medicinal chemists and clinical researchers.
• Contribute to manuscript writing and grant applications.
• Mentor junior team members and contribute to the overall research environment.

Qualifications

• PhD or MD in Molecular Biology, Cell Biology, Biochemistry, Genetics, or a related field.
• Strong background in DNA repair, cancer biology, or chromatin biology is preferred.
• Experience with mammalian cell culture, protein purification, and molecular cloning.
• Excellent communication skills and ability to work both independently and in a team-oriented environment.
• Demonstrated ability to publish in peer-reviewed journals.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA). $72,000.00 - $76,385.00