Postdoctoral Fellowship in CAR T-cell research

National Cancer Institute; Bethesda (MD); On-site; USD 65,000 - 90,000; Full time

Job summary

National Cancer Institute in Bethesda, MD, seeks a Chimeric antigen receptor T-cell Immunotherapy Postdoctoral Fellow to advance translational cancer immunotherapy.

The successful candidate will work in the lab of James N. Kochenderfer, employing flow cytometry, sequencing, and murine models to develop and optimize CAR T-cell therapies, with additional work on bispecific antibodies. A doctoral degree and strong publication record are required.

Qualifications

• Applicants must have a doctoral degree with four years or less of postdoctoral experience.
• Experience with flow cytometry and working with mice.
• Record of publication in immunology, gene therapy, or molecular biology.
• Good writing and presentation skills are required for selection.

Responsibilities

• Study cancer immunotherapy by genetically modifying T cells to express chimeric antigen receptors (CARs).
• Work on bispecific antibodies as planned.
• Develop new CARs, identify CAR targets, and optimize gene therapy technologies.

Skills

Flow cytometry

Mouse models

T-cell immunology

Publication record

Education

Doctoral degree

Tools

Next-gen sequencing

Gene therapy techniques

Job description

Position Title: Chimeric antigen receptor T-cell Immunotherapy Postdoctoral Fellowship at NIH

Position Description: One fully funded postdoctoral position is available for a highly motivated individual to study cancer immunotherapy at the National Institutes of Health, National Cancer Institute. The position is in the lab of James N. Kochenderfer. Projects will focus on developing new therapies by genetically modifying T cells to express chimeric antigen receptors (CARs). Work on bispecific antibodies is also planned. This position is most suitable for an applicant interested in translational research rather than basic immunology research. A wide variety of activities are carried out by the group including development of new CARs, identifying new CAR targets, and optimizing gene therapy technologies. Techniques used include cellular immunology including flow cytometry, various types of next-generation sequencing, murine models of hematological malignancies, design and construction of new CARs, and clinical trials of T-cell therapies. Ample funding and core laboratory support are available. Applicants must have experience with flow cytometry and working with mice. Experience in T-cell immunology is desirable but not required. Interested candidates must have a doctoral degree with four years or less of postdoctoral experience. A record of publication in immunology, gene therapy, or molecular biology along with good writing and presentation skills are required for selection. This position is subject to a background investigation. This postdoctoral position offers very stable and generous funding from NIH intramural funds. More information is available at this link: https://ccr.cancer.gov/staff-directory/james-n-kochenderfer

Employer Name: National Cancer Institute, Center for Cancer Research, Surgery Branch

Position Location: Bethesda, Maryland, U.S.A.