Postdoctoral Associate - Cell and Gene Therapy

Baylor College of Medicine; Town of Texas (WI); On-site; USD 63,000 - 64,000; Full time

Job summary

Baylor College of Medicine in Houston, TX, seeks a Postdoctoral Associate in Cell and Gene Therapy to join the Center for Advanced Innate Cell Therapy within the Texas Children's Cancer Center. The project aims to develop and test CAR-redirected immunotherapies for pediatric solid tumors, using knockout/knock-in screens to identify regulators of immune activity.

The lab offers state-of-the-art facilities and a highly interactive environment for scholars in basic, translational, and clinical

Qualifications

• MD or PhD in Basic Science, Health Science, or a related field.
• No experience required.
• PhD in immunology, genetic engineering, or related fields.
• Strong knowledge of tumor immunology principles.
• Ability to assess scRNAseq datasets and flow cytometry.
• Understanding and practicing genetic engineering techniques (CRISPR-Cas9, transfection, viral transduction, transposition).
• Viral particle assembly.
• Excellent aseptic cell culture technique.
• Enthusiasm and a willingness to learn in a fast-paced environment.
• Strong organizational skills and interpersonal communication (verbal and written).

Responsibilities

• Designs and conducts the experiments with mentor and team.
• Analyzes data and presents results at weekly meetings.
• Records details in electronic laboratory notebook.
• Writes technical reports and manuscripts for publication.
• Performs other duties as assigned.

Skills

Molecular biology

Tumor immunology

Flow cytometry

scRNA-seq data interpretation

Viral vector engineering

Aseptic cell culture

Interpersonal communication

Education

MD or PhD in Basic Science/Health Science or related field

PhD in immunology or genetic engineering

Job description

Postdoctoral Associate - Cell and Gene Therapy

Job Title: Postdoctoral Associate - Cell and Gene Therapy Division: Pediatrics Work Arrangement: Onsite only Location: Houston, TX Salary Range: $63,480 - $64,356 FLSA Status: Exempt Work Schedule: Monday – Friday, 8 a.m. – 5 p.m.

Summary

A Postdoctoral Associate position in cancer immunology and immunotherapy is available at the Center for Advanced Innate Cell Therapy within the Texas Children's Cancer Center. The project aims to develop and test novel CAR-redirected immunotherapy for pediatric solid tumors. In particular, gene knockout and knock-in screens will be applied to discover and therapeutically target novel regulators of the immune effector cell antitumor activity. The lab offer outstanding state-of-the-art, recently expanded laboratory facilities and a highly interactive environment for basic, translational, and clinical investigators. Postdoctoral Associate must have a recent PhD degree and an expertise in molecular biology and tumor immunology with a documented record of productivity.
Baylor College of Medicine typically follows similar to the NIH stipulated stipend guidelines for Postdoctoral Associates.

Job Duties

• Designs and conducts the experiments related to the project with the help of the mentor and other team members.
• Analyzes the data and present the evolving results at weekly laboratory meetings and research seminars.
• Records the details of the experiments in an electronic laboratory notebook.
• Writes technical reports and manuscripts for publication in peer-reviewed scientific journals.
• Performs other job-related duties as assigned.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Ph.D. in immunology, genetic engineering, or related fields.
• Great fund of knowledge of tumor immunology principles.
• Ability to assess scRNAseq datasets and highly parametric flow cytometry.
• Understanding and practicing genetic engineering techniques (transfection, retroviral / lentiviral transduction, transposition, CRISPR-Cas9).
• Viral particle assembly.
• Excellent aseptic cell culture technique.
• Enthusiasm and a willingness to learn in a fast-pace, collaborative environment.
• Strong organizational skills, record keeping, and interpersonal communication skills (verbal and written).

Baylor College of Medicine fosters diversity among its students, trainees, faculty, and staff as a prerequisite to accomplishing our institutional mission and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.