Postdoctoral Fellow - Multimodal Technologies & Complex Human Models, Regev and Chen Labs

F. Hoffmann-La Roche AG; South San Francisco (CA); On-site; USD 100,000 - 107,000; Full time

Job summary

Genentech in California is seeking a highly motivated Postdoctoral Fellow to develop novel single cell and spatial omics platforms for screening next generation human in vitro models. You will advance computational methods and work with AI to interpret high-dimensional data, contributing to high-impact publications and drug discovery efforts.

This hands-on role requires a PhD with proven first-author work, strong molecular biology and bioinformatics skills, and the ability to collaborate across

Qualifications

• Hands-on experience in molecular biology, functional genomics, single cell genomics, and/or spatial omics.
• Strong computational experience with single cell genomic or spatial data analysis; fluent in Python or similar.
• Demonstrated ability to publish first-author work in leading journals or on bioRxiv.

Responsibilities

• Develop scalable measurement tools to acquire molecular, imaging and functional readouts from perturbation studies in in vitro complex models.
• Design and execute multimodal functional genomics screens to investigate disease mechanisms at cellular and tissue levels.
• Collaborate with computational biologists and AI scientists to integrate and interpret multimodal data and explore predictive modeling strategies.
• Collaborate across labs and present work to project teams and contribute to high-impact publications.
• Join Genentech’s postdoctoral program to pursue fundamental questions while building methods that drive drug development.

Skills

Single cell genomics

Spatial omics

Imaging

Bioengineering

Biophysics

Python

Communication

Education

PhD in related field

Job description

Why Genentech We advance science so that we all have more time with the people we love. A Postdoctoral Fellow position is available for a highly motivated and independent scientist to develop novel single cell and spatial omics platforms to screen next generation complex human in vitro models in order to accelerate target discovery. The candidate will develop new experimental and computational methods to characterize cellular responses to perturbations and generate high-dimensional datasets that enable a deeper understanding of disease biology. This is a hands on position for a scientist passionate about assay development as well as engaging in state of the art computational tools, including and especially AI. You will join a collaborative, cross disciplinary environment and will have the opportunity to contribute to high impact scientific publications.

The Opportunity

• Novel Assay Development: Develop scalable measurement tools to acquire molecular, imaging and functional readouts from perturbation studies in in vitro complex models
• Large Scale Screening: Design and execute multimodal functional genomics screens to investigate mechanisms underlying disease cellular and tissue states.
• Computational Methods: Collaborate with computational biologists and AI scientists to develop approaches for integrating and interpreting multimodal data, and explore predictive modeling strategies to power Lab in the Loop.
• Collaborative Research: Collaborate productively with experimental and computational scientists across labs and departments, present your work to project teams, and contribute to high impact scientific publications.
• Professional Development: Join Genentech’s postdoctoral training program, which provides an outstanding environment and the opportunity to pursue fundamental scientific questions while building methods that drive breakthrough discoveries in drug development.

Who You Are

Ph D with a proven track record of excellence in single cell genomics, spatial omics, imaging, bioengineering, biophysics, quantitative biology, or a related field, with hands on experimental expertise. Must have advanced at least one key research project as evidenced by a first author paper published or accepted in a leading peer reviewed journal, or on Biorxiv. Strong hands on experience in molecular biology, functional genomics, single cell genomics, and/or spatial omics. Experience with complex mammalian cell culture, with experience in iPSC cell models, organoids or 3D cultures a plus. Computational experience spanning single cell genomic or spatial data analysis, with a track record of programming fluently in Python or a comparable language. Independent scientist with outstanding communication skills, a strong passion and commitment to science, who works well within a team.

Postdoc Program Elevate your research career to new heights with Genentech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph D graduates to conduct world class research, publish in top tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world class seminars, professional development workshops, and networking opportunities.

The expected salary range for this position based on the primary location of California is $100,000 to $106,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company’s policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company’s policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.