Postdoctoral Fellow — HIV Antibody & Immunogen Design

PeopleAdmin, Inc.; California (MO); On-site; USD 52,000 - 68,000; Full time

Job summary

The Scripps Research Institute in La Jolla, CA, invites applications for a NIH-funded Postdoctoral Associate in the Department of Immunology and Microbial Science and the CHAVI-ID. Working under Prof.

Jiang Zhu, you will study the evolution of HIV-1 broadly neutralizing antibodies in natural infection and help develop HIV-1 vaccine immunogens for in vivo evaluation. Candidates should hold a PhD in biophysics, biochemistry, structural biology, immunology or vaccinology; experience with antibody

Qualifications

• Must possess a doctoral degree.
• A pending doctoral degree may be considered with approval of the PI.

Responsibilities

• Isolate HIV-1 neutralizing antibodies from patient or immunized samples using single-cell technologies and NGS.
• Determine lineage patterns of HIV-1 neutralizing antibodies over time during infection and vaccination.
• Design and optimize HIV-1 immunogens including epitope-scaffolds, gp140 trimers, and nanoparticles.
• Analyze immunized animal samples to evaluate HIV-1-specific B-cell responses and protection.

Education

Doctoral degree in biophysics/biochemistry/structural biology/immunology/vaccinology

Job description

The Scripps Research Institute in La Jolla, CA, invites applications for a NIH-funded Postdoctoral Associate in the Department of Immunology and Microbial Science and the CHAVI-ID. Working under Prof.

Jiang Zhu, you will study the evolution of HIV-1 broadly neutralizing antibodies in natural infection and help develop HIV-1 vaccine immunogens for in vivo evaluation. Candidates should hold a PhD in biophysics, biochemistry, structural biology, immunology or vaccinology; experience with antibody