Postdoctoral Associate

PeopleAdmin, Inc.; California (MO); On-site; USD 52,000 - 68,000; Full time

Job summary

The Scripps Research Institute in La Jolla, CA, invites applications for a NIH-funded Postdoctoral Associate in the Department of Immunology and Microbial Science and the CHAVI-ID. Working under Prof.

Jiang Zhu, you will study the evolution of HIV-1 broadly neutralizing antibodies in natural infection and help develop HIV-1 vaccine immunogens for in vivo evaluation. Candidates should hold a PhD in biophysics, biochemistry, structural biology, immunology or vaccinology; experience with antibody

Qualifications

• Must possess a doctoral degree.
• A pending doctoral degree may be considered with approval of the PI.

Responsibilities

• Isolate HIV-1 neutralizing antibodies from patient or immunized samples using single-cell technologies and NGS.
• Determine lineage patterns of HIV-1 neutralizing antibodies over time during infection and vaccination.
• Design and optimize HIV-1 immunogens including epitope-scaffolds, gp140 trimers, and nanoparticles.
• Analyze immunized animal samples to evaluate HIV-1-specific B-cell responses and protection.

Education

Doctoral degree in biophysics/biochemistry/structural biology/immunology/vaccinology

Job description

Department Name: Integrative Structural and Computational Biology

Position Type:

Position Type: Full Time

Position Title

Position Title Postdoctoral Associate

Position Summary:

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Research Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Research Associates do not have consulting privileges.

Location:

Location: California

Additional Information:

An NIH -funded postdoctoral position is available for highly motivated candidates to study the evolution of HIV -1 broadly neutralizing antibodies (bNAbs) in natural infection, and to develop HIV -1 vaccine immunogens for in vivo evaluation, in the laboratory of Prof. Jiang Zhu, Department of Immunology and Microbial Science, Department of Structural and Computational Biology, and Scripps Center for HIV / AIDS Vaccine Immunology & Immunogen Discovery ( CHAVI -ID), The Scripps Research Institute, La Jolla, CA.

Potential projects may involve (1) isolating HIV -1 neutralizing antibodies from patient samples or immunized animal samples using single-cell technologies and next-generation sequencing ( NGS ); (2) determining the lineage patterns of HIV -1 neutralizing antibodies longitudinally during infection and vaccination; (3) computationally designing & optimizing HIV -1 immunogens including epitope-scaffolds, gp140 trimers, and nanoparticles; (4) analyzing immunized animal samples with various assays to evaluate HIV -1-specific B-cell responses and protection.

Physical Requirements:

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

Basic Qualifications:

Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

Preferred Qualifications:

Successful candidates will have a recent Ph.D. in biophysics, biochemistry, structural biology, immunology, and vaccinology. Training in animal immunization or prior experience with antibody and vaccine research will be a plus.

Compensation:

Job Closing Date:

Open Until Filled Yes

Job Posting Category

Job Posting Category Postdoctoral

EEO Statement

The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.

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