Postdoctoral Fellow: Cancer Biology & IDH Glioma Research

Mass General Physicians Organization; Boston (MA); On-site; USD 65,000 - 90,000; Full time

Job summary

Massachusetts General Brigham Cancer Center seeks a postdoctoral fellow to study how mutations in IDH alter glioma biology and how this knowledge can guide therapy. The lab uses a mix of CRISPR screening, gene induction/knockdowns, protein biochemistry, and mouse models in collaboration with Harvard programs.

Candidates should have a MD or PhD with strong molecular and cellular biology training and a track record in translational cancer research.

Qualifications

• Postdoctoral candidate with MD or PhD and strong background in molecular and cellular biology.
• Experience with cancer biology or translational cancer research is highly valued.
• Familiarity with in vitro and in vivo experimental techniques is required.

Responsibilities

• Investigate how IDH mutations affect glioma biology and treatment responses.
• Perform in vitro and in vivo experiments including CRISPR screening, gene knockdowns, and mouse modeling.
• Collaborate with multiple research programs and translational partners.

Skills

CRISPR screening

Gene induction

Knockdowns

Protein biochemistry

Transgenic mouse modeling

Flow cytometry

Bioinformatics

Computational biology

Molecular biology

Cellular biology

Education

MD or PhD

Tools

CRISPR

Flow Cytometry

Bioinformatics software

Job description

Massachusetts General Brigham Cancer Center seeks a postdoctoral fellow to study how mutations in IDH alter glioma biology and how this knowledge can guide therapy. The lab uses a mix of CRISPR screening, gene induction/knockdowns, protein biochemistry, and mouse models in collaboration with Harvard programs.

Candidates should have a MD or PhD with strong molecular and cellular biology training and a track record in translational cancer research.