Postdoctoral Fellow

University of Pennsylvania Perelman School of Medicine; Pennsylvania; On-site; USD 55,000 - 75,000; Full time

Job summary

University of Pennsylvania Perelman School of Medicine seeks a postdoctoral fellow to join a CRI-funded immunotherapy atlas project. The role involves leading data integration across atlas labs, applying flow cytometry, scRNA(+TCR)-seq, proteomics, and spatial analyses to build a comprehensive immune landscape resource.

The candidate will develop data‑driven hypotheses, work independently and within a team, and gain experience mastering cutting-edge technologies for translational immuno-oncology

Qualifications

• Successful candidates will have a PhD, MD, or MD/PhD degree, experience in immunology and/or cancer biology, a strong record of productivity, and a demonstrated ability to work independently and as a team.

Responsibilities

• Lead the project in the Wherry lab and integrate data across two additional CRI-Immunotherapy Atlas labs.
• Perform experimental approaches including flow cytometry, scRNA (+TCR)-seq, proteomics, and spatial analysis.
• Generate data‑driven hypotheses and become a collaborative scientific leader.

Skills

Immunology

Cancer biology

Data analysis

Independent work

Team collaboration

Education

PhD or MD or MD/PhD degree

Tools

Flow cytometry

scRNA-seq

TCR-seq

Proteomics

Spatial analysis

Job description

University of Pennsylvania: Postdoctoral Positions: Perelman School of Medicine Postdoctoral

Location

University of Pennsylvania, Perelman School of Medicine

Open Date

Aug 07, 2026

The Wherry lab, in the Department of Systems Pharmacology and Translational Therapeutics, has an opening for a postdoctoral fellow to join a CRI-funded research project. This position is part of a larger CRI Initiative to establish a data resource that will enable data-driven innovation in immunotherapy and address the translational gap between preclinical models and clinical trials. This Immunotherapy Altas will incorporate comprehensive immune landscapes across commonly used mouse models as well as how these landscapes are altered when immunotherapy perturbations are applied. The goal for this position is to contribute to the establishment of this resource and to use it to address data-driven hypotheses that are generated based on analyses of this resource.

The postdoctoral fellow will lead this project in the Wherry lab and be instrumental in integrating similar data across two additional CRI-Immunotherapy Atlas labs. Experimental approaches to address the tumor-immune microenvironment will include flow cytometry, scRNA (+TCR)-seq, proteomics, and spatial analysis.

This position is an excellent opportunity to learn how to master cutting-edge technologies, leverage large datasets, generate data-driven hypotheses, and become a strong collaborative scientific leader.

Qualifications

Successful candidates will have a PhD, MD, or MD/PhD degree, experience in immunology and/or cancer biology, a strong record of productivity, and a demonstrated ability to work independently and as a team.