Postdoctoral Biophysical Chemist — AI-Driven Drug Discovery

Eli Lilly and Company; Indianapolis (IN); On-site; USD 58,000 - 123,000; Full time

Job summary

Eli Lilly and Company in Indianapolis is seeking a Postdoctoral Biophysical Chemist to join a cross-functional team advancing small molecule discovery. You will apply integrative biophysical and computational methods to accelerate medicine development.

The role requires a PhD in a related field, strong NMR and MD experience, and the ability to build AI-informed models. This is an onsite, fixed-term position up to 2 years with competitive benefits.

Qualifications

• Ph.D. in Biophysical Chemistry, Biophysics, Computational Chemistry, or related field.
• Strong foundation in biomolecular NMR with expertise in protein structure and dynamics.
• Demonstrated experience integrating experimental data with molecular dynamics.

Responsibilities

• Join cross-functional team to apply integrative biophysical and computational methods.
• Run biophysical and biomolecular NMR experiments.
• Integrate experimental data with MD and free energy calculations.
• Develop AI methods for analyzing simulations and build structural models.
• Automate workflows to maximize throughput and reproducibility.
• Stay current with AI/ML methods in drug discovery.
• Present progress to internal and external teams.
• Collaborate with discovery scientists to advance leads.

Skills

Biophysical Chemistry

Biophysics

Biomolecular NMR

Molecular dynamics

Python

HPC

Education

Ph.D. in Biophysical Chemistry, Biophysics, Computational Chemistry, or related field

Tools

Python

Molecular dynamics software

NMR data analysis tools

Quantum mechanics calculations

Job description

Eli Lilly and Company in Indianapolis is seeking a Postdoctoral Biophysical Chemist to join a cross-functional team advancing small molecule discovery. You will apply integrative biophysical and computational methods to accelerate medicine development.

The role requires a PhD in a related field, strong NMR and MD experience, and the ability to build AI-informed models. This is an onsite, fixed-term position up to 2 years with competitive benefits.