Postdoc Scientist: Protein Formulations & Biophysics

100 Eli Lilly and Company; Indianapolis (IN); On-site; USD 58,000 - 123,000; Full time

Job summary

Eli Lilly and Company in Indianapolis, IN, seeks a postdoctoral scientist to advance protein and peptide therapeutics. You will translate mechanistic insights into robust formulation strategies and collaborate across drug substance, product, structural biology, and analytical sciences.

The role requires a Ph.D. in Biophysics, Biochemistry, Pharmaceutical Sciences, Chemical or Biomedical Engineering, with strong communication and publication track record.

Qualifications

• Ph.D. in Biophysics, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, Biomedical Engineering or closely related discipline.
• Strong foundation in protein biophysics, structural biology, biologic formulation science, or analytical characterization of peptide/protein therapeutics.

Responsibilities

• Investigate the physical stability of various modalities under formulation parameters (pH, concentration, ionic strength, etc.).
• Apply biophysical and analytical techniques to characterize molecular interactions and assess impact on structure, viscosity, and stability.
• Develop mechanistic or kinetic models linking formulation and PK/PD outcomes.
• Stay current with literature to guide experimental design.
• Collaborate with cross‑functional teams across drug substance, drug product, structural biology, analytical sciences, biophysical characterization, formulation, computational modeling, and translational pharmacology.
• Present findings at conferences and publish in peer‑reviewed journals.

Skills

Biophysics

Biochemistry

Protein science

Formulation science

PK/PD concepts

Data analysis

Communication

Education

Ph.D. in Biophysics/Biochemistry/Pharmaceutical Sciences/ Chemical/Biomedical Engineering

Tools

Bio‑NMR

SAXS

X-ray crystallography

Cryo-EM

SEC‑MALS

ITC

Job description

Eli Lilly and Company in Indianapolis, IN, seeks a postdoctoral scientist to advance protein and peptide therapeutics. You will translate mechanistic insights into robust formulation strategies and collaborate across drug substance, product, structural biology, and analytical sciences.

The role requires a Ph.D. in Biophysics, Biochemistry, Pharmaceutical Sciences, Chemical or Biomedical Engineering, with strong communication and publication track record.