Postdoctoral Associate - Liver Disease and Development

Baylor College of Medicine; Town of Texas (WI); On-site; USD 63,000 - 70,000; Full time

Job summary

Baylor College of Medicine in Houston, TX, invites applications for a Postdoctoral Associate in the Division of Molecular and Human Genetics to study Alagille syndrome. The position focuses on dissecting the SOX4/SOX9 transcriptional network that governs biliary development and exploring therapeutic angles for cholestatic diseases.

The successful candidate will work on a newly funded NIH R01 project, design and execute experiments, and communicate findings through presentations and manuscripts.

Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.
• Experience in mouse genetics essential, preferably in liver development and disease.
• Expertise in molecular biology, biochemistry, and/or bioinformatic analysis is desired.
• Has strong publication record and available to begin promptly.

Responsibilities

• Designs and conducts experiments related to Alagille syndrome and will assist the PI in reporting the results.
• Summarizes the research findings.
• Performs statistical analyses to determine the significance of the observations.
• Communicates the results with collaborators via email exchange and virtual presentations.
• Participates in preparing grant applications.
• Performs other job-related duties as assigned.

Skills

Mouse genetics

Molecular biology

Biochemistry

Bioinformatic analysis

Publication record

Education

MD or PhD in Basic Science

Job description

Job Title: Postdoctoral Associate - Liver Disease and Development

Division: Molecular and Human Genetics

Work Arrangement: Onsite only

Location: Houston, TX

Salary Range: $63,480 - $70,000

FLSA Status: Exempt

Work Schedule: Monday – Friday, 8 a.m. – 5 p.m.

Summary

A Postdoctoral Associate position is available in the laboratory of Hamed Jafar-Nejad, M.D., in the Department of Molecular & Human Genetics, Baylor College of Medicine. The laboratory uses cell culture, Drosophila and mouse genetics to identify and characterize genetic modifiers of human developmental disorders, in hopes of shedding light on disease pathophysiology and establishing new therapeutic strategies.

The Postdoctoral Associate will design and execute experiments related to Alagille syndrome and interpret the results. The Postdoctoral Associate will be responsible for summarizing the findings in the form of presentations and manuscripts. The Postdoctoral associate should have expertise in mouse models of human disease, preferably liver disease, and he/she will be responsible for the proposed experiments and will assist the PI (Dr. Jafar-Nejad) in reporting the results.

The Postdoctoral Associate will lead a newly funded NIH R01 project dissecting the SOX4/SOX9 transcriptional regulatory network that governs biliary development in Alagille syndrome and advancing the therapeutic potential of targeting this network in ALGS and other cholestatic diseases. There may also be opportunities to contribute to related ongoing projects in the lab.

This is a full-time position available immediately.

Baylor College of Medicine typically follows similar to the NIH stipulated stipend guidelines for Postdoctoral Associates.

• Designs and conducts experiments related to preclinical studies on Alagille syndrome and will assist the PI in reporting the results.
• Summarizes the research findings.
• Performs statistical analyses to determine the significance of the observations. Works will be based on models and techniques already established in the laboratory, the postdoc will likely need to set up new techniques and potentially establish new disease models as well, depending on how the project proceeds.
• Communicates the results with collaborators via email exchange and virtual presentations.
• Participates in preparing grant applications.
• Performs other job-related duties as assigned.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Recent Ph.D. graduate or an M.D. with relevant research experience.
• Experience in mouse genetics is essential, preferably in the context of liver development and disease.
• Expertise in molecular biology, biochemistry, and/or bioinformatic analysis is desired.
• Has strong publication record and available to begin promptly.

Baylor College of Medicine fosters diversity among its students, trainees, faculty, and staff as a prerequisite to accomplishing our institutional mission and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.