Postdoc: Tumor Immune Regulation & Microenvironment

Boehringer Ingelheim GmbH; Ridgefield (CT); Sur place; USD 72 000 - 88 000; Plein temps

Résumé du poste

Boehringer Ingelheim in Ridgefield, CT seeks a Postdoctoral Fellow to advance our tumor immune regulation portfolio. You will design independent projects, build advanced human tumor models, and work with a multidisciplinary team to uncover mechanisms of immune suppression in the tumor microenvironment.

You will develop ex-vivo platforms, employ CRISPR-based approaches, and aim for publications and potential patents.

Qualifications

• Ph.D. in tumor immunology, cancer biology, immunology, or related field with up to 3 years postdoctoral experience.
• Strong publication record demonstrating independence, creativity, and innovation.
• Deep knowledge of tumor microenvironment biology and anti-tumor immunity.
• Experience with tumor-immune cell co-cultures and advanced systems (3D or ex-vivo).
• Experience with genetic perturbation techniques including CRISPR-based approaches.
• Ability to design, optimize, and execute complex research projects and workflows.
• Experience with multi-omics, high-content imaging, or spatial biology workflows is preferred.

Responsabilités

• Design and conduct independent research on immune suppression in human tumors.
• Develop multicellular co-culture systems with primary immune cells and tumor cells.
• Establish ex-vivo tumor models from patient materials and tissue platforms.
• Apply CRISPR-based perturbation to interrogate suppressive pathways.
• Integrate multidimensional readouts to characterize immune suppression mechanisms.
• Collaborate with researchers inside and outside Boehringer Ingelheim.
• Publish first-author papers and contribute to patents as applicable.

Connaissances

Tumor immunology

Immunology

Scientific independence

Publications

Formation

Ph.D. in tumor immunology or related field

Outils

CRISPR-based approaches

3D/ex-vivo models

Description du poste

Boehringer Ingelheim in Ridgefield, CT seeks a Postdoctoral Fellow to advance our tumor immune regulation portfolio. You will design independent projects, build advanced human tumor models, and work with a multidisciplinary team to uncover mechanisms of immune suppression in the tumor microenvironment.

You will develop ex-vivo platforms, employ CRISPR-based approaches, and aim for publications and potential patents.