Postdoc: Structural Biology & Target Discovery

Thesgc; Chapel Hill (NC); On-site; USD 50,000 - 70,000; Full time

Job summary

A leading research institution in Chapel Hill is seeking a Postdoctoral Research Associate to join a NIH-funded initiative aimed at accelerating Alzheimer’s drug discovery. The role involves designing protein production workflows, characterizing protein interactions, and determining protein structures. Ideal candidates hold a PhD in Biological Sciences, are proficient in molecular biology techniques, and have experience in protein purification and assay development. This position offers a dynamic research environment focused on therapeutic innovation.

Qualifications

• Demonstrated proficiency in molecular biology, including high-throughput cloning.
• Skilled in protein purification equipment, high-speed centrifuges.
• Expertise in developing biochemical assays with fluorescence polarization.

Responsibilities

• Design recombinant protein production workflows.
• Develop assays to characterize protein-ligand interactions.
• Determine protein structures using X-ray crystallography.

Skills

Molecular biology

Recombinant protein production

Protein purification

Biochemical assays

Biophysical assays

Education

PhD in Biological Sciences or Chemical Biology

Tools

Fast Protein Liquid Chromatography (FPLC)

Isothermal titration calorimetry (ITC)

Surface plasmon resonance (SPR)

Job description

A leading research institution in Chapel Hill is seeking a Postdoctoral Research Associate to join a NIH-funded initiative aimed at accelerating Alzheimer’s drug discovery. The role involves designing protein production workflows, characterizing protein interactions, and determining protein structures. Ideal candidates hold a PhD in Biological Sciences, are proficient in molecular biology techniques, and have experience in protein purification and assay development. This position offers a dynamic research environment focused on therapeutic innovation.