Post-Doc Research Associate - Williams Lab

University of North Carolina at Chapel Hill; Chapel Hill (NC); On-site; USD 52,000 - 66,000; Full time

Job summary

The University of North Carolina at Chapel Hill seeks a Post-Doc Research Associate in the Williams Lab to advance studies on chromatin remodeling inhibitors. The role involves hands-on protein purification, binding and kinetic analyses, and structural biology techniques in a collaborative research environment.

Ideal candidates hold a PhD in biological or chemical sciences with demonstrated experience in biochemistry, protein purification, and possibly tissue culture.

Qualifications

• PhD in Biological or Chemical Sciences is required.
• Experience with protein purification is required.
• Experience with biochemistry and tissue culture is preferred.

Responsibilities

• Develop peptide/small molecule inhibitors of chromatin remodeling complex.
• Perform protein purification binding and kinetic analyses.
• Conduct structural biology and FRET/BRET measurements.

Skills

Protein purification

Biochemistry

Tissue culture

Education

PhD in Biological or Chemical Sciences

Job description

Department:

Pathology Lab Med - Research - 413804

Posting Open Date:

08/25/2026

Open Until Filled:

Yes

Position Type:

Postdoctoral Scholar

Position Title:

Post-Doc Research Associate - Williams Lab

Vacancy ID:

PDS004954

Full-time/Part-time:

Full-Time Temporary

Hours per week:

40

FTE:

1

Work Location:

Chapel Hill, NC

Position Location:

North Carolina, US

Hiring Range:

Dependent on Experience and Qualifications

Estimated Duration of Appointment:

12 Months

Be a Tar Heel!:

A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation’s top public universities and is among is the top ten research universities in the nation for federal research expenditures as well as for federally funded social and behavioral sciences research and development. Here at Carolina, our highly skilled postdocs play a vital role in our research enterprise and towards our overall commitment to research excellence. Across many disciplines, postdocs contribute to the intellectual vitality of the University. They provide innovative ideas and perspectives, foster a stimulating research environment and advance knowledge within their fields. Postdocs are crucial members of our scientific research workforce, contributors to our research outputs and an important reason why Carolina is one of the leading public research institutions in the country. UNC-Chapel Hill offers postdocs comprehensive medical and vision coverage, paid leave, and benefits and services that support professional development and a healthy work/life balance. Chapel Hill regularly ranks as one of the best college towns and best places to live in the United States, a reputation guided by the diverse social, cultural, recreation and professional opportunities that span the campus and community.

Primary Purpose of Organizational Unit:

Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education and research.

Patient care: We promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.

Education: We prepare tomorrow`s healthcare professionals and biomedical researchers from all backgrounds by facilitating learning within innovative and integrated curricula and team-oriented interprofessional education to ensure a highly skilled workforce.

Research: We develop and support a rich array of outstanding health sciences research programs, centers and resources. We provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our university to support outstanding research. We foster programs in the areas of basic, translational, mechanistic and population research.

Position Summary:

The Postdoctoral Research Associate will be involved in developing peptide/small molecule inhibitors of chromatin remodeling complex. Work will include protein purification binding and kinetic analyses, structural biology, and FRET/BRET measurements.

Minimum Education and Experience Requirements:

PhD in the Biological or Chemical Sciences.

Required Qualifications, Competencies, and Experience:

Experience in protein purification.

Preferred Qualifications, Competencies, and Experience:

Experience with biochemistry and tissue culture as well as an interest in translation research and applying for fellowship funding are highly desirable.