Postdoc, Immunology: Senolytic Therapy for Fibrotic Lung

Scorpion Therapeutics; San Francisco (CA); On-site; USD 150,000 - 190,000; Full time

Job summary

Scorpion Therapeutics is seeking a scientist to lead the development of a precision senolytic approach targeting fibrotic lung disease. You will establish senescence models spanning primary human cells, iPSC-derived cells, and in vivo fibrosis models, and identify markers to distinguish pathological senescent cells from healthy tissue.

You will engineer immune-based strategies to selectively eliminate senescent cells, evaluate efficacy in human tissue and in vivo models, and collaborate across

Qualifications

• PhD in Immunology, Cell Biology, Molecular Biology, Aging Biology or a closely related field.
• Demonstrated experience with cellular senescence and fibrosis or aging biology.
• Strong publication record demonstrating scientific productivity and independence.

Responsibilities

• Establish and characterize models of cellular senescence relevant to fibrotic lung disease across primary human cells, iPSC-derived cells and in vivo models.
• Identify and validate cell-surface markers distinguishing pathological senescent cells from healthy tissue with safety considerations.
• Develop immune effector–based strategies to selectively eliminate senescent cells in the fibrotic lung.
• Evaluate senolytic efficacy and its impact on fibrosis in human tissue and in vivo models.
• Collaborate with cross-functional teams and external partners; present findings at conferences and publish as first author.

Education

PhD in Immunology

PhD in Cell Biology

PhD in Molecular Biology

Aging Biology

Publication-driven research

Job description

Scorpion Therapeutics is seeking a scientist to lead the development of a precision senolytic approach targeting fibrotic lung disease. You will establish senescence models spanning primary human cells, iPSC-derived cells, and in vivo fibrosis models, and identify markers to distinguish pathological senescent cells from healthy tissue.

You will engineer immune-based strategies to selectively eliminate senescent cells, evaluate efficacy in human tissue and in vivo models, and collaborate across