Postdoc: CRISPR & dTAG-KI Mouse Models

Baylor College of Medicine; Houston (TX); On-site; USD 54,000 - 73,000; Full time

Job summary

The Center for Drug Discovery at Baylor College of Medicine in Houston, Texas, seeks a Postdoctoral Research Associate to develop and characterize dTAG knock-in mouse models for biomedical and pharmacological research. The role uses CRISPR/Cas9 genome editing, molecular biology, and animal experiments to study drug-metabolizing enzymes in vivo.

It provides training in genome engineering, conditional protein degradation, and translational pharmacology, with stipend guidance typical for NIH

Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Responsibilities

• Collaborates with core facilities to design CRISPR/Cas9 genome-editing strategies for dTAG-KI mice.
• Collects blood and tissues at designated time points.
• Evaluates target-protein expression via Western blotting.
• Performs animal dosing and experimental treatments.
• Maintains mouse colony management, breeding, and recordkeeping.
• Analyzes data and prepares figures, reports, and manuscripts.

Skills

Independent work

Analytical skills

Scientific communication

Education

MD or Ph.D. in Basic Science or Health Science

PhD, MD or equivalent doctoral degree in molecular biology, genetics, pharmacology, biomedical sciences

Tools

CRISPR/Cas9

Western blotting

In vivo mouse work

Job description

The Center for Drug Discovery at Baylor College of Medicine in Houston, Texas, seeks a Postdoctoral Research Associate to develop and characterize dTAG knock-in mouse models for biomedical and pharmacological research. The role uses CRISPR/Cas9 genome editing, molecular biology, and animal experiments to study drug-metabolizing enzymes in vivo.

It provides training in genome engineering, conditional protein degradation, and translational pharmacology, with stipend guidance typical for NIH