Post-Doctoral Fellow – Mamedov Lab

Colonial Group; Philadelphia (Philadelphia County); On-site; USD 52,000 - 70,000; Full time

Benefits offered by this job

Benefits package

Job summary

The Wistar Institute in Philadelphia is seeking a highly motivated Postdoctoral Fellow to lead projects in T cell biology, cancer immunology, and genome editing. The role focuses on TCR ligand discovery, γδ T cell engineering, and cancer cell stress sensing to advance novel immunotherapies.

Applicants should have expertise in T cell biology, genomics, or related areas and a track record of productive research.

Qualifications

• PhD in immunology, cancer biology, or a closely related field.
• Experience with CRISPR screening or genome editing.
• Strong publication record and ability to communicate findings clearly.

Responsibilities

• Lead high-impact projects on TCR tumor ligand discovery and γδ T cell biology.
• Perform CRISPR screening and engineering of human γδ T cells.
• Characterize stress-remodeled cancer cells and develop immunotherapy approaches.

Skills

T cell biology

Cancer immunology

CRISPR screening

Genomics

Gene editing

In vitro cancer models

Education

PhD in immunology or related field

Tools

None

Job description

The laboratory of Dr. Murad Mamedov at The Wistar Institute is recruiting a Postdoctoral Fellow. The Mamedov Lab uses CRISPR screens and functional genomics to understand how the human immune system detects and kills cancer cells. We focus on understanding how human γδ T cells sense cellular stress in tumors, with the goal of developing novel and broadly accessible immunotherapies.

We are seeking a highly motivated Postdoctoral Fellow to lead high-impact projects focused on T cell receptor (TCR) tumor ligand discovery, CRISPR screening and engineering of human γδ T cells, and T cell detection of stress-remodeled cancer cells. This work will build on and significantly expand beyond our published work on human γδ T cell recognition and killing of cancer cells (Nature, PMID: 37648854). The successful candidate will have expertise in one or more of the following: T cell biology, cancer immunology, in vitro cancer models, genomics, or gene editing.

We offer a competitive salary and an excellent benefits package.

The Wistar Institute is in Philadelphia, in the heart of the University of Pennsylvania campus. Wistar provides resources for cutting-edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities. The Wistar Institute is a world leader in early-stage discovery science in the areas of cancer, immunology, and infectious disease. Wistar is committed to accelerating research advances from bench to bedside through brilliant science and distinctive approaches to collaboration among scientific investigators and academic and industry partners. Wistar’s dynamic environment supports the advancement of discoveries that will change the future of human health.

For more information about The Wistar Institute visit our website at www.wistar.org.