Research Assistant - McGinnis Lab

Colonial Group; Philadelphia (Philadelphia County); Sur place; USD 42 000 - 62 000; Plein temps

Résumé du poste

The Wistar Institute invites applications for Research Assistants to join the Vaccine and Immunotherapy Center (VIC) led by Dr. Christopher McGinnis.

The role encompasses tissue processing for flow cytometry and single-cell genomics, molecular cloning, tumor transplantation, sequencing library prep, and high-throughput screening in breast cancer and other metastasis-related projects. Successful candidates will have a science-focused bachelor’s degree, strong communication, and organizational

Qualifications

• Bachelor's degree in a science-related field is required.
• Experience in cancer biology or immunology is preferred and highly valued.
• Strong communication and organizational skills are essential.

Responsabilités

• Process tissues for flow cytometry and single-cell genomics assays.
• Perform molecular cloning and tumor transplantation surgeries.
• Conduct nucleic acid analyses and prepare libraries for sequencing.
• Run high-throughput drug screen experiments using ex vivo tissue slice cultures.
• Provide technical assistance to trainees and faculty in molecular and cellular biology experiments and animal studies.

Connaissances

Cancer biology

Immunology

Molecular biology

Cell culture

Flow cytometry

Mouse colony maintenance

Surgical techniques

Next-generation sequencing

PCR

DNA cloning

Formation

Bachelor's degree in science-related field

Outils

PCR

DNA cloning

Next-generation sequencing library preparation

Description du poste

The Wistar Institute has two openings for highly motivated Research Assistants to work in the laboratory of Dr. Christopher McGinnis as part of the Vaccine and Immunotherapy Center (VIC) at The Wistar Institute.

The McGinnis lab is interested in how tumors interact with the immune system during metastasis and developing new single-cell genomics modalities to interrogate mechanisms of pro-metastatic immune remodeling. Focusing on breast cancer, osteosarcoma, and other tumor types with lung metastatic tropism, the McGinnis Lab aims to improve our basic understanding of how tumors spread and translate these insights into the development of anti-metastatic immunotherapies.

The responsibilities of successful candidates will involve:

• Processing tissues for flow cytometry and single-cell genomics assays
• Molecular cloning and tumor transplantation surgeries
• Nucleic acid analyses and next-generation sequencing library preparation
• High-throughput drug screen experiments using ex vivo tissue slice cultures
• Technical assistance to post-doctoral and pre-doctoral students with molecular and cellular biology experiments, and in animal studies.

A bachelor's degree in a science-related field, or equivalent combination of education and experience, is required. Excellent communication and organizational skills are essential. Candidates will receive personalized training as required. Competitive applicants will have strong motivation to learn and to work in a collaborative environment. Experience in the following areas is preferred: cancer biology, immunology, molecular biology (PCR, DNA cloning, etc), cell culture, flow cytometry, mouse colony maintenance and surgical techniques, and/or next-generation sequencing.

The Wistar Institute is a world leader in early-stage discovery science in the areas of cancer, immunology, and infectious disease. Wistar is committed to accelerating research advances from bench to bedside through brilliant science and distinctive approaches to collaboration among scientific investigators and academic and industry partners. Wistar's dynamic environment supports the advancement of discoveries that will change the future of human health.

The Wistar Institute is located in the University City area of Philadelphia, in the heart of the University of Pennsylvania Campus. Wistar provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities.

We offer a competitive salary and excellent benefits package.

For more information about The Wistar Institute visit our website at www.wistar.org.