Post-Doctoral Fellow

The University of Kansas

Lawrence (KS)

On-site

USD 53,000 - 65,000

Full time

13 days ago

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Job summary

The Center of BioModular Multi-Scale Systems for Precision Medicine (CBMM) at The University of Kansas invites applications for a post-doctoral fellow to advance nanotechnology for structural determinations of proteins. This NSF-funded two-year project focuses on resistive pulse sensing with novel plastic in-plane nanopore sensors and integrated exopeptidase reactors.

Candidates with a Ph.D. in biomedical or mechanical engineering or chemistry are welcome.

Qualifications

Ph.D. in biomedical engineering, mechanical engineering, or chemistry at appointment time.
A Ph.D. in hand is required for the Postdoctoral Researcher title.

Responsibilities

35%: conduct experiments to secure resistive pulse signatures for 20 amino acids using plastic in-plane nanopore sensors.
20%: build an integrated plastic system with an exopeptidase reactor coupled to the nanopore sensor to determine amino acid composition of peptides.
15%: fabricate in-plane nanopore sensors via modified injection molding with thermal fusion bonding and explore surface chemistries including TRIS modification.
10%: monitor graduate students on RPS measurements and exopeptidase activity.
10%: write peer‑reviewed papers on detection/identification of amino acids via RPS and online detection post‑exopeptidase action.
5%: attend and present at weekly/group meetings and national/international meetings as scheduled.
5%: participate in NSF-mandated outreach activities to the public and school children.

Skills

Nanopore sensing

Resistive Pulse Sensing

Machine learning

Education

Ph.D. in Biomedical Engineering

Ph.D. in Mechanical Engineering

Ph.D. in Chemistry

Tools

Nanopore fabrication

Injection molding

Thermal fusion bonding

Surface modification chemistries

Job description

Position Overview

The Center of BioModular Multi-Scale Systems for Precision Medicine (CBMM) at the University of Kansas (College of Liberal Arts & Sciences and School of Engineering) is seeking qualified candidates for a post-doctoral fellow position to work on a nationally-funded project focused on developing nanotechnology for structural determinations of proteins.

This position has funding for up to two years.

Job Description

35% - Using our plastic in-plane nanopore sensors using established techniques in the laboratory (injection molding and thermal fusion bonding), the PD will conduct experiments to secure resistive pulse signatures for the 20 amino acids.

20% - Build an integrated system in a plastic using injection molding that will consist of a solid-phase exopeptidase reactor coupled to the dual in-plane nanopore sensor to determine the amino acid composition of input peptides.

15% - Fabricate in-plane nanopore sensors via a modified injection molding process with an assembly process that uses thermal fusion bonding. This category also involves looking at different surface modification chemistries, including TRIS modification.

10% - Monitoring graduate students on the RPS measurements of single amino acid molecules and the action or exopeptidases when surface immobilized.

10% - Writing peer-reviewed papers covering topics on the detection and identification of single amino acids using RPS and the on-line detection of amino acids following exopeptidase action on peptides.

5% - Attend weekly group meetings and weekly sub-group meetings and make presentations at each of these meeting on an irregular basis (depends on scheduling). Also, make presentations on research work at national/international meetings at the discretion of the PI (Soper).

5% - Participate in outreach activities to the general public and school children on the basic concepts of protein/peptide/amino acid chemistry and RPS sensing. These activities are mandated by the funding source (NSF).

Required Qualifications

Ph.D. in any of the following disciplines conferred at the time of appointment: biomedical engineering, mechanical engineering, or chemistry.

NOTE: To be appointed at the Postdoctoral Researcher title or equivalent title, it is necessary to have the Ph.D. in hand.

Appointments made without a diploma or certified transcript indicating an earned doctorate are conditional hires and are appointed on an acting basis not to exceed 6-months.

This position requires a formal degree in the cited discipline area(s) to ensure that candidates have advanced knowledge, analytical skills and professional competencies necessary to perform the duties of the position. The level of degree is commonly recognized as the standard qualification for similar roles in the public and private sector, ensuring that the university remains competitive with industry aligned practices, enhances collaboration with external partners, and supports the delivery of services and programs that meet professional and market-driven expectations.

Preferred Qualifications