Post Doc Research Assistant

Purdue University; West Lafayette (IN); On-site; USD 52,000 - 68,000; Full time

Job summary

Purdue University seeks a Postdoctoral Fellow to advance NIH-funded research on inhalation toxicology and immunotoxicology. The work combines cell culture and mouse models to study how pollutants drive lung disease in susceptible populations, using advanced mass spectrometry to uncover mechanisms.

The candidate will perform in vitro and in vivo exposures, supporting translational insights and future leadership in toxicology. Office: West Lafayette, IN.

Qualifications

• PhD in a relevant field and strong interest in mechanistic toxicology.
• Experience in cell culture, mouse handling, in vitro/in vivo exposures, and basic molecular biology techniques.
• Background in lung biology or immunology is preferred.

Responsibilities

• Perform mechanistic toxicology research using cell culture and mouse models.
• Investigate particulate matter, engineered nanomaterials, and environmental pollutants on pulmonary injury and immune dysfunction.
• Apply mass spectrometry techniques to study biological mechanisms.
• Collaborate across teams to advance the lab's goals.

Skills

Cell culture

Mouse handling

In vitro exposure

In vivo exposure

Molecular biology techniques

Western blot

RT-PCR

Flow cytometry

Lung biology

Immunology

Education

PhD in toxicology, environmental science, immunology, cell biology, or biochemistry

Tools

Mass spectrometry

Job description

We are seeking a highly motivated Postdoctoral Fellow to join an NIH-funded research program focused on inhalation toxicology and immunotoxicology, with an emphasis on the cellular and molecular mechanisms of lung disease in susceptible subpopulations. Research in the lab focuses on unique mechanisms of toxicity which occur in prevalent human subpopulations that contribute to susceptibility following exposures. To perform our studies, we integrate cell culture systems and mouse models to investigate particulate matter, engineered nanomaterials, and other environmental pollutants induction of pulmonary injury, immune dysregulation, and lung disease pathogenesis. Ongoing projects involve mechanisms such as lipid signaling, particle-biomolecular interactions, regulation of inflammation, and immune dysfunction. The laboratory utilizes a variety of techniques but uniquely employs cutting edge mass spectrometry approaches to assess biological mechanisms. The overarching goal of the research program is to identify distinct deficiencies in susceptible subpopulations following exposures that can be leveraged for therapeutic benefit.

Candidates must hold a PhD from an accredited institution in toxicology, environmental science, immunology, cell biology, biochemistry, or a closely related field, and demonstrate a strong interest in mechanistic toxicology research. Candidates must be highly motivated, passionate about research, and have a desire to be a future leader within the field of toxicology. Experience in cell culture, mouse handling, in vitro/in vivo exposures, and basic molecular biology techniques such as western blot, RT-PCR, flow cytometry, etc. is beneficial. A background in lung biology or immunology is preferred.

Professor of Toxicology, School of Health Sciences

Assistant Dean of Research Development and Innovation,

College of Health and Human Sciences

School of Health Sciences
Purdue University
915 Mitch Daniels Blvd
LillyHall of Life Sciences B454
West Lafayette, IN 47907
Office: [phone]