Platform Engineering & Operations Lead

Denali-Therapeutics; South San Francisco (CA); On-site; USD 159,000 - 207,000; Full time

Benefits offered by this job

401(k)

Healthcare coverage

ESPP

Job summary

Denali Therapeutics in South San Francisco, CA, seeks a senior Platform Engineering leader to own the operational agenda, drive platform strategy, and oversee an enterprise AI infrastructure. You will build governance, manage change, and sustain delivery across multi-site platforms with emphasis on regulated environments.

You will lead a team of engineers and partners, ensuring reliable operations, incident response, and continuous improvement within a SOX/GxP framework.

Qualifications

• 9+ years of IT across platform engineering, infra, ITSM, or IT ops.

Responsibilities

• Lead IT Infrastructure as a function, owning the operational agenda, operating rhythms, and standards.

Skills

Leadership

ITSM

Platform engineering

GxP compliance

SOX ITGC

Architecture governance

Vendor management

AIOps / Observability

Communication

Multi-cloud

Tools

Workato

Databricks

Reltio

AWS

GCP

Azure

ITIL v4

SAP

MES

Job description

Denali Therapeutics in South San Francisco, CA, seeks a senior Platform Engineering leader to own the operational agenda, drive platform strategy, and oversee an enterprise AI infrastructure. You will build governance, manage change, and sustain delivery across multi-site platforms with emphasis on regulated environments.

You will lead a team of engineers and partners, ensuring reliable operations, incident response, and continuous improvement within a SOX/GxP framework.