Physician Scientist, Translational Genetics - Immunology

Initial Therapeutics, Inc.; Village of Tarrytown (NY); On-site; USD 173,000 - 284,000; Full time

Job summary

A leading biotechnology company is seeking a Physician Scientist to join their Immunology Therapeutic Area Genetics (TAG) team. The role involves leveraging genetic data to identify new therapeutic targets for autoimmune diseases, collaborating across disciplines, and driving innovative cancer research. Candidates should ideally possess an MD or MD/PhD, with substantial experience in large-scale genetic studies.

Benefits

Comprehensive health and wellness programs

Fitness centers

Equity awards

Annual bonuses

Paid time off

Qualifications

• Experience using WES/GWAS datasets, RNA-Seq, proteomics.
• Proficiency in computational cancer research.
• 3+ years experience in oncology-related research.

Responsibilities

• Design and execute studies integrating human genetics.
• Collaborate with teams to develop drug discovery pipelines.
• Analyze omics datasets for drug target identification.

Skills

Innovation in genetic studies

Multidisciplinary collaboration

Education

MD

MD/PhD preferred

Job description

We are looking for an extremely talented Physician Scientist to join our Immunology Therapeutic Area Genetics (TAG) team. Within the RGC, the Immunology TAG team is using large-scale human exome sequencing for discovery and validation of new therapeutic targets in autoimmune and other immune-mediated diseases. You will be responsible for designing and executing studies integrating large-scale human genetics and multidimensional omics datasets derived from RGC and public resources in the immunology space to identify new targets for inflammatory and autoimmune diseases and accelerate their transition to novel therapeutics. You will collaborate with various RGC teams and with pre-clinical and clinical development teams at Regeneron to catalyze therapeutic development for genetically validated targets in immunologic diseases.

In this role, a typical day might include the following:

• Deploying computational methods for integrating and interpreting such information to more effectively identify/prioritize drug targets illuminated by genetic association data.
• Working closely with other members of the Oncology and other TAG teams, Analytic Genetics, Sequencing, and GIDE to acquire omics datasets.
• Acquiring, organizing, and analyzing omics datasets derived from within the RGC, from collaborative partnerships, and/or from publicly available resources.

This job might be for you if you can/have:

• Bring innovative thinking to large-scale genetic studies and analysis.
• A strong work ethic and proactive approach to providing solutions that foster scientific collaborations and drive projects forward within Regeneron.
• Work closely with multidisciplinary teams to characterize the functional consequences of discovered disease gene variants and ensure objectives are met across therapeutic areas.

To be considered for this opportunity, you must have:

• Demonstrated expertise in solid tumor cancer biology, genetics, and mechanisms; familiarity with large genetic studies that deliver novel genetic findings and medically relevant gene discoveries.
• Ability to manage and collaborate within a multi-disciplinary team to discover and develop oncology-related drug discovery pipelines.
• MD required; MD/PhD preferred, with >3 years of experience using WES/GWAS datasets, RNA-Seq, proteomics, metabolomics, and other large-scale platforms for genomic/proteomics research. Proficiency in computational cancer research is highly encouraged.

#RGCAG

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We offer an inclusive and diverse culture with comprehensive benefits, including health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels.

Regeneron is an equal opportunity employer. All qualified applicants will receive consideration regardless of race, color, religion, sex, nationality, ethnicity, civil status, age, citizenship, sexual orientation, disability, genetic information, familial or marital status, gender identity or reassignment, military or veteran status, or any other protected characteristic under applicable law. Reasonable accommodations will be provided to qualified applicants with disabilities unless undue hardship occurs.

For U.S.-based roles, the salary range is $173,500 - $283,100 annually, in accordance with U.S. law. For roles in Japan and/or Canada, salary ranges are provided per local law and currency. Please consult your recruiter for details regarding salaries and benefits in your location.

Note that background checks are part of the recruitment process and will be conducted according to the laws of the country where the position is based, to verify identity, right to work, educational qualifications, etc.