Physician Scientist, Translational Genetics - Immunology

Regeneron Pharmaceuticals; United States; Remote; USD 173,000 - 284,000; Full time

Job summary

A leading company in biopharmaceuticals is seeking an experienced Physician Scientist to drive the discovery of novel therapeutic targets within their Immunology Therapeutic Area. The role involves integrating large-scale genetics and omics data to support drug development for autoimmune diseases. Candidates should possess a strong background in cancer biology, genetics, and multi-disciplinary collaboration, along with an MD or MD/PhD and relevant experience.

Benefits

Health and wellness programs

Fitness centers

Equity awards

Annual bonuses

Paid time off

Qualifications

• Expertise in solid tumor cancer biology and genetics.
• Experience with WES/GWAS datasets and other large-scale platforms.
• Ability to manage and collaborate in multidisciplinary teams.

Responsibilities

• Designing and executing studies to identify new therapeutic targets.
• Acquiring and analyzing omics datasets for insights.
• Collaborating with multiple teams to advance drug discovery.

Skills

Innovative thinking

Proactive solutions

Collaborative teamwork

Education

MD

MD/PhD

Job description

We are looking for an extremely talented Physician Scientist to join our Immunology Therapeutic Area Genetics (TAG) team. Within the RGC, the Immunology TAG team is using large-scale human exome sequencing for discovery and validation of new therapeutic targets in autoimmune and other immune-mediated disease. Youwill be responsible for designing and executing studies integrating large scale human genetics and multidimensional omics datasets derived from RGC and public resources in the immunology space to identify new targets for inflammatory and auto-immune diseases and accelerate target transition to novel therapeutics. You will collaborate with various RGC teams and with pre-clinical and clinical development teams at Regeneron to catalyze therapeutic development for genetically-validated targets in immunologic diseases.

In this role, a typical day might include the following:

• Deploying computational methods for integrating and interpreting such information so as to more effectively identify/prioritize drug targets illuminated by genetic association data.

• Working closely with other members of the Oncology and other TAG teams, Analytic Genetics, Sequencing, and GIDE to acquire omics datasets.

• Acquire, organize and analyze omics datasets derived from within the RGC, from collaborative partnerships and/or from publicly-available resources.

This job might be for you if you can/have

• Bring innovative thinking to large-scale genetic studies and analysis.

• A strong work ethic and are proactive in providing solutions to foster scientific collaborations and drive projects forward within Regeneron.

• Work closely with multidisciplinary teams to characterize the functional consequences of discovered disease gene variants and ensure objectives are being met across the therapeutic areas.

To be considered for this opportunity, you must have ademonstrated expertise in solid tumor cancer biology, genetics and mechanisms; familiarity with large genetic studies that deliver novel genetic findings and medically relevant gene discoveries; and demonstrated ability to manage and collaborate in a multi-disciplinary team, to discover and evolve oncology-related drug discovery pipelines. MD Required, MD/PhD preferred with >3 years of experience in the use of WES/GWAS datasets, RNA-Seq, proteomics, metabolomics and other large-scale platforms for genomic/proteomics proficiency in computational cancer research are particularly encouraged to apply.

#RGCAG

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)

$173,500.00 - $283,100.00