PET Neuroimaging Scientist — Translational Radioligand

UW School of Medicine and Public Health; Madison (WI); On-site; USD 80,000 - 100,000; Full time

Job summary

The Nirschl and Kolb laboratories at the University of Wisconsin–Madison invite applications for a Scientist I or II to contribute to the discovery and development of novel PET imaging tracers targeting pathological protein aggregates in neurodegenerative diseases.

The role involves setting up and executing tissue-based assays, autoradiography, radioligand binding, and immunoassays to evaluate compound binding in human and animal tissue.

Qualifications

• Advanced experience in tissue-based assay development including autoradiography and radioligand binding assays using tissue slices and purified proteins.
• Proficiency in biochemical extraction and purification of pathological proteins from brain tissue.
• Experience with competitive binding and displacement assays to quantify tracer specificity and affinity.

Responsibilities

• Assists with the identification of research problems and development of methodologies.
• Conducts literature reviews and prepares reports for dissemination.
• Contributes to invention disclosures and IP documentation for new imaging agents.

Skills

Tissue-based assays

Autoradiography

Radioligand binding

SPR

Biochemical extraction

Immunohistochemistry

Data analysis

Education

PhD in bioanalytical science or related field

Job description

The Nirschl and Kolb laboratories at the University of Wisconsin–Madison invite applications for a Scientist I or II to contribute to the discovery and development of novel PET imaging tracers targeting pathological protein aggregates in neurodegenerative diseases.

The role involves setting up and executing tissue-based assays, autoradiography, radioligand binding, and immunoassays to evaluate compound binding in human and animal tissue.