Payroll Administrator

TriNetX; Cambridge (MA); Hybrid; USD 70,000 - 100,000; Full time

Job summary

TriNetX is seeking a Payroll Administrator responsible for accurate and timely processing of all payroll activities for U.S. and international employees.

You will ensure compliance with federal, state, and local regulations while partnering with Finance, HR and Operations in a fast-paced, scaling organization. You will manage weekly and monthly payroll cycles, validate timesheets and deductions, reconcile outputs, and support tax reporting and audits.

Qualifications

• Bachelor’s degree or higher in a relevant field.
• 3+ years of payroll processing experience in multi-state environment.
• Strong understanding of payroll regulations, tax laws, and wage/hour standards.
• Experience with modern payroll software (ADP, Dayforce, Vistra Global).

Responsibilities

• Prepare and process payroll for U.S. and international employees; coordinate cycles.
• Validate timesheets, deductions, bonuses, and other pay adjustments.
• Reconcile payroll outputs and support month-end close entries.

Skills

Payroll processing

Multi-state payroll

Regulatory compliance

Payroll software

Education

Bachelor’s degree or higher in Accounting/Finance/Business

Tools

ADP Workforce Now

Dayforce

Vistra Global

HRIS integrations

Job description

This position reports to our global HQ in Cambridge, MA and is hybrid with 2-3 days onsite.

Who We Are:

TriNetX connects healthcare organizations and researchers across the globe so they can see what’s happening in real patient populations—not guesses, not simulations.

Our aim is simple and ambitious: Provide a clear path to trustworthy answers, whether your goal is to create promising new therapies, publish groundbreaking research, or improve health outcomes.

We keep identifiable data where it belongs—inside more than 11,000+ clinical sites across 20+ countries—preserving security, provenance, and granularity. Our trusted partnerships with providers ensure high-fidelity data, and a properly governed linkage back to individual patients.

At TriNetX, we enable life sciences, healthcare, and academic institutions to strengthen human health—with data you can trace, evidence you can defend, and answers you can trust.

Who We Are Looking For:

The Payroll Administrator is responsible for the accurate and timely processing of all payroll activities for TriNetX’s U.S. and international employees. This role ensures compliance with federal, state, and local regulations while supporting internal stakeholders in Finance, HR and Operations. The ideal candidate is detail oriented, highly organized, and able to work in a fast paced, scaling organization.

What You Will Be Doing:

Payroll Processing

• Prepare and process weekly, semi-monthly payroll for U.S. employees and coordinate monthly payroll cycles for international entities.
• Maintain payroll records including new hires, terminations, compensation changes, and benefit deductions.
• Validate timesheets, commissions, bonuses, and other pay related adjustments.
• Reconcile payroll prior to transmission and validate all outputs.

Compliance & Reporting

• Ensure compliance with all federal, state, and local payroll laws and regulations.
• File payroll tax reports and coordinate with external tax partners as needed.
• Support annual and quarterly reporting, including W-2, 1099, and audit requests.
• Maintain confidentiality and adhere to data privacy standards.

Systems & Process Management

• Administer payroll systems (e.g., Dayforce, Vistra Global, or company specific tools) and coordinate integrations with HRIS and accounting software.
• Identify and implement process improvements to increase payroll accuracy and efficiency.
• Manage payroll GL mappings and support Finance with month end close entries and reconciliations.

Employee Support

• Serve as primary point of contact for payroll related inquiries.
• Provide clear and timely communication regarding payroll policies, deductions, tax withholding, and paycheck questions.
• Collaborate with HR on benefits, leave programs, and employee lifecycle changes.

What You Bring to TriNetX:

• Bachelor’s degree or higher in Accounting, Finance, Business, or equivalent experience.
• 3+ years of payroll processing experience in a multi-state environment.
• Strong understanding of payroll regulations, tax laws, and wage/hour standards.
• Experience with modern payroll software (ADP Workforce Now, Dayforce, Vistra Global, etc.).
• Exceptional attention to detail and strong analytical skills.
• Ability to handle confidential information with discretion.

Preferred

• Experience supporting global payroll in EMEA or APAC regions.
• CPP (Certified Payroll Professional) or FPC certification.
• Prior experience in a high growth tech or healthcare data company.