Organic Synthesis Chemist

Synergy Bioscience company; Dallas, Northern (TX, KY); On-site; USD 110,000 - 150,000; Full time

Benefits offered by this job

Health care plan

Paid time off

Training & development

Job summary

Synergy Bioscience is seeking a seasoned Organic Chemist to lead enantiomeric synthesis programs in Dallas. You will design multi-step routes and collaborate with analytical teams to advance projects while maintaining GMP documentation and compliance.

The role requires a Master’s or PhD in Organic Chemistry and 7+ years of hands-on experience in enantiomeric compound synthesis, with strong knowledge of stereochemistry, NMR, LC-MS, and chromatographic methods.

Qualifications

• Master’s degree or PhD in Organic Chemistry or related field.
• 7+ years hands-on experience in organic synthesis of enantiomeric compounds.
• Experience with multi-step synthesis and route optimization.
• Strong knowledge of stereochemistry and analytical techniques.
• Experience documenting GMP-compliant work.

Responsibilities

• Design and perform multi-step syntheses to produce enantiomeric chemical entities.
• Develop and optimize synthetic routes to improve yield, purity, and scalability of enantiomeric chemicals.
• Document experimental procedures, data, and results accurately in lab notebooks and reports, following good documentation practices.
• Collaborate with analytical scientists to support project goals and timeline.
• Ensure compliance with safety, GMP, and regulatory requirements in all laboratory activities.
• Troubleshoot synthetic scheme challenges, characterization data, and reaction conditions, and propose innovative solutions.

Skills

Enantiomeric synthesis

Multi-step synthesis

Stereochemistry

Analytical data interpretation

GMP documentation

Collaboration

HPLC/LC-MS/NMR experience

Education

Master’s or PhD in Organic Chemistry or related field

Tools

HPLC

GC-MS

LC-MS

NMR

Job description

Synergy Bioscience is a contract research, development, manufacturing, testing, and consulting organization serving pharmaceutical, biopharmaceutical, and medical device clients. The company supports product development through analytical, testing, and regulatory expertise, helping clients move complex programs forward with scientific rigor, quality, and precision.

In this role, you will contribute to chemistry programs focused on the development of enantiomeric chemical entities. This is an opportunity to apply deep organic synthesis expertise in a collaborative laboratory environment, working closely with cross-functional scientific partners to advance project goals while maintaining high standards for quality, documentation, and compliance.

Responsibilities

• Design and perform multi-step organic syntheses to produce enantiomeric chemical entities.
• Develop and optimize synthetic routes to improve yield, purity, and scalability of enantiomeric chemicals.
• Document experimental procedures, data, and results accurately in lab notebooks and reports, following good documentation practices.
• Collaborate with analytical scientists to support project goals and timeline.
• Ensure compliance with safety, GMP, and regulatory requirements in all laboratory activities.
• Troubleshoot synthetic scheme challenges, characterization data, and reaction conditions, and propose innovative solutions.

• Master’s degree or PhD in Organic Chemistry or a related field.
• 7+ years of hands-on experience in the organic synthesis of enantiomeric compounds.
• Experience with multi-step organic synthesis and route optimization.
• Deep knowledge of stereochemistry, enantiomeric synthesis, reaction mechanisms, synthetic methodologies, and analytical techniques.
• Hands-on experience documenting work in GMP-compliant laboratory environments.
• Experience working closely with analytical scientists, including interpreting characterization data, coordinating method support, and partnering on project timelines.
• Hands-on experience with HPLC, GC-MS, and LC-MS; experience with chiral chromatography and NMR is a plus.

• Health Care Plan (Medical, Dental & Vision)
• Paid Time Off (Vacation, Sick & Public Holidays)
• Training & Development