Onsite Senior Medical Director, Clinical Development

Kardigan; Princeton (NJ); On-site; USD 250,000 - 420,000; Full time

Benefits offered by this job

On-site in Princeton

Competitive compensation

Job summary

Kardigan is seeking an Executive Medical Director, Clinical Development to act as a senior physician-scientist and sponsor Medical Monitor for cardiovascular programs. This role requires medical credibility with investigators, ethics committees, IDMCs, and health authorities, and involves direct collaboration with CROs, Clinical Operations, and data safety functions.

The position emphasizes deep clinical judgment, protocol content ownership, and rigorous safety oversight throughout trial

Qualifications

• MD (or equivalent medical degree) required; board certification and meaningful clinical practice preferred.
• Experience leading medical monitoring in Phase 2/3 programs and safety reviews.
• Strong ability to interact with investigators, IRBs/Ethics Committees, and health authorities.

Responsibilities

• Own the scientific and clinical content of the protocol, including endpoint selection and safety provisions.
• Lead the medical monitoring of trials and data review for safety and efficacy.
• Provide medical input to regulatory submissions and internal safety plans.
• Maintain up-to-date therapeutic area knowledge and translate insights into protocol design decisions.
• Serve as sponsor Medical Monitor and lead the Safety Review Team materials and reviews.

Skills

MD/DO

Clinical development

Medical monitoring

Safety assessment

Regulatory submissions

Education

MD or equivalent medical degree

Job description

Kardigan is seeking an Executive Medical Director, Clinical Development to act as a senior physician-scientist and sponsor Medical Monitor for cardiovascular programs. This role requires medical credibility with investigators, ethics committees, IDMCs, and health authorities, and involves direct collaboration with CROs, Clinical Operations, and data safety functions.

The position emphasizes deep clinical judgment, protocol content ownership, and rigorous safety oversight throughout trial